NCT07427485Completed
Cognitive Rehabilitation With Immersive Virtual Reality (IVR) in Schizophrenia: a Pilot Randomized Waiting List Controlled Feasibility Study
Source: ClinicalTrials.gov · Last updated 15 Jun 2026
Brief summary (registry, in English)
Virtual reality-based rehabilitation has recently gained increasing attention in the field of cognitive rehabilitation, allowing patients to engage in simulated real-life scenarios within a safe and controlled setting. The feasibility and safety of immersive VR-based cognitive rehabilitation in individuals with schizophrenia is currently insufficiently explored. This study seeks to evaluate whether immersive immersive virtual reality-based rehabilitation can be safely and practically implemented in a community psychiatric setting. The study also aims to explore preliminary effects on negative symptoms, cognitive performance, and global functioning compared with treatment as usual in a waiting-list control group.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 40 (actual)
- First submitted
- 17 Feb 2026
- Start date
- 11 Mar 2025
- Primary completion date
- 11 Mar 2026
- Lead sponsor
- Azienda Sanitaria Locale Napoli 3 Sud, UOCSM Torre del Greco
- Diseases
- Schizophrenia
- NCT number
- NCT07427485
What you commit to
- Study type: Interventional
- Participants enrolled: 40
- From 11 Mar 2025 to the primary completion date, 11 Mar 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Concomitant intellectual disability or neurological disorders (e.g., neurodegenerative disorders, Parkison's disease, brain cancer) that may impair the ability to undergo cognitive rehabilitation
Other illness
- Acute phase of illness
Other
- Recent substance use (less than six months)
- With a recent (less than six weeks from the enrolling date) symptom exacerbation, hospitalization or change in pharmacotherapy
Who the study is looking for
- Individuals with Schizophrenia/Schizoaffective Disorder (DSM-5-TR)
- Age 18-67 years
- Chronic phase of illness
- Able to provide a valid informed consent
Age in the registry: 18 years to 67 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Azienda Sanitaria Locale Napoli 3 Sud Unità Operativa Complessa Salute Mentale Torre del Greco/Ercolano Coordinator of this site? Confirm its status | Torre del Greco | Italy | Unknown status |
Related publications
- Cognitive rehabilitation with immersive virtual reality in schizophrenia: A randomized waiting list-controlled study.Schizophr Res Cogn · 2026 · PMID 42568860
This page is information, not medical advice. Discuss any trial with your doctor.