NCT07427537Recruiting
Exploration of Circulating microRNAs as Biomarkers of Chemo-induced Peripheral Neuropathy: a Study in Cancer Patients
Source: ClinicalTrials.gov · Last updated 23 Feb 2026
Brief summary (registry, in English)
This study aims to find out whether certain molecules in the blood, called microRNAs, are linked to how often and how severely people develop nerve damage from chemotherapy. The investigators will look at patients receiving cancer drugs known to affect the nerves, such as paclitaxel (used for lung cancer) and oxaliplatin (used for colorectal cancer).
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 90 (estimated)
- First submitted
- 5 Jan 2026
- Start date
- 29 Jan 2026
- Primary completion date
- 31 Jul 2028
- Lead sponsor
- University Hospital, Clermont-Ferrand
- Diseases
- Lung cancer, Colorectal cancer
- NCT number
- NCT07427537
What you commit to
- Study type: Interventional
- Planned participants: 90
- From 29 Jan 2026 to the primary completion date, 31 Jul 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Neurodegenerative disease (e.g., Parkinson's, Alzheimer's, etc.),
- History of stroke,
Other
- Pre-existing neuropathy (QLQ-CIPN20 sensory score ≥ 15/100),
- Pain (NRS ≥ 4/10),
- Pregnant or breastfeeding women,
- Patients under guardianship, curatorship, deprived of liberty, or under legal protection
Who the study is looking for
- Patient treated for colorectal cancer and scheduled to receive oxaliplatin-based adjuvant chemotherapy for at least 6 cycles, or
- Patient treated for lung cancer and scheduled to receive paclitaxel-based chemotherapy for at least 4 cycles.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CHU Clermont-Ferrand Coordinator of this site? Confirm its status | Clermont-Ferrand | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.