NCT07427849Recruiting
Observational Study on the Use of Ultrasound to Recognize Superficial Endometriosis in a Specific Area of the Pelvis (the Uterosacral Ligaments)
Ultrasound Diagnosis of Superficial Endometriosis of LUS (Uterosacral Ligaments): Definition of a Laparoscopically Validated Ultrasound Cut-off.
Source: ClinicalTrials.gov · Last updated 25 Feb 2026
Brief summary (registry, in English)
An observational, prospective, multicenter study conducted on patients of childbearing age undergoing laparoscopic surgery for early-stage benign or malignant gynecological disease. The study does not include changes to the standard care pathway.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 64 (estimated)
- First submitted
- 17 Feb 2026
- Start date
- 17 Feb 2026
- Primary completion date
- Aug 2026
- Lead sponsor
- Casa di Cura Dott. Pederzoli
- Diseases
- Endometriosis
- NCT number
- NCT07427849
What you commit to
- Study type: Observational
- Planned participants: 64
- From 17 Feb 2026 to the primary completion date, Aug 2026
- 4 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- previous pelvic surgery
Other illness
- advanced malignant disease (\>Stage I for endometrium and cervix, \> Stage II for ovary)
- PID or other pelvic inflammatory diseases
Other
- presence of endometriosis deeply infiltrating the posterior compartment. This may interfere with the interpretation of uterosacral ligament (LUS) thickness as a specific marker of superficial endometriosis
- technical impossibility of performing a transvaginal ultrasound (patient virgo, patient refusal).
- incomplete ultrasound evaluation of the uterosacral ligaments for anatomical reasons or for the presence of endometriosis nodules from other sites with partial involvement of the LUS (uterosacral ligament).
- pelvic organ prolapse
- medical emergencies (ovarian torsion, hemoperitoneum)
- postmenopausal patients
Who the study is looking for
- patients who need to undergo gynecological surgery with a laparoscopic approach for benign pathology (endometriosis, uterine fibroids, adenomyosis, chronic pelvic pain, benign ovarian cysts) or non-advanced malignant pathology (stage I endometrium and cervix, stage I and II ovary).
- patients who performed a level II gynecological ultrasound with an experienced operator in the preoperative pathway.
- technical possibility of performing a transvaginal ultrasound and the patient's willingness to undergo such an investigation.
- patients of childbearing age (18 - 50 years).
- Signing of informed consent.
Age in the registry: 18 years to 50 years · Sex: Female · Does not accept healthy volunteers
Sites (4)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Policlinico Abano Terme Coordinator of this site? Confirm its status | Abano Terme | Italy | Not yet recruiting |
| Policlinico Universitario Federico II Coordinator of this site? Confirm its status | Naples | Italy | Not yet recruiting |
| Ospedale P. Pederzoli Casa di Cura Privata S.p.A. Coordinator of this site? Confirm its status | Peschiera del Garda | Italy | Recruiting |
| Presidio ospedaliero-universitario Santa Maria della Misericordia - Azienda Sanitaria Universitaria Friuli Centrale Coordinator of this site? Confirm its status | Udine | Italy | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.