NCT07427940Recruiting
Omic Profile in Autism Spectrum Disorder: From Cellular Level Towards Future Treatments
Source: ClinicalTrials.gov · Last updated 23 Feb 2026
Brief summary (registry, in English)
This is an interventional non pharmacological study in pediatric patientis affected by Autism Spectrum Disorder. It ams to create a collection of iPSCs and hiNSCs derived from deeply characterized ASD patients, to omics-characterize the cells, and to study the behavioral pattern of microglia-like cells in the onset of ASD.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 100 (estimated)
- First submitted
- 19 Dec 2024
- Start date
- 31 Aug 2024
- Primary completion date
- 31 Aug 2026
- Lead sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
- Diseases
- Autism
- NCT number
- NCT07427940
What you commit to
- Study type: Interventional
- Planned participants: 100
- From 31 Aug 2024 to the primary completion date, 31 Aug 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Exclusion criteria for Group 1 will be: having a defined genetic diagnosis or an overall clinical presentation strongly suggestive for a syndromic condition. For this definition we will apply the criteria ASD associated with at least one of the following: \>=3 facial anomalies, \>=1 major/\>=2 minor malformation (following EUROCAT classification), clinical issue affecting \>=2 systems. Children showing such phenotypes but having no current genetic diagnosis could not be included in the study. Patients with a syndromic presentation and confirmed genetic diagnosis will be included in the Syndromic Group 2.
Other
- No standardized test to establish diagnosis
- Parents refusing to complete the consent form
- Impossible blood sample collection.
Who the study is looking for
- Defined ASD diagnosis according to DSM-5 criteria
- Age 3-15 years
- Informed consent signed by the guardians/legal representatives.
Age in the registry: 3 years to 15 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Foundation IRCCS Carlo Besta Neurological Institute Coordinator of this site? Confirm its status | Milan | Italy | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.