NCT07428187Recruiting
Snacking Effects on the Brain Response to Foods and Satiety During Dieting
Source: ClinicalTrials.gov · Last updated 23 Mar 2026
Brief summary (registry, in English)
This study plans to learn more about how different types of snacks may affect brain processes relating to eating behaviors during a diet intervention.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 70 (estimated)
- First submitted
- 12 Feb 2026
- Start date
- 5 Mar 2026
- Primary completion date
- 31 Mar 2028
- Lead sponsor
- University of Colorado, Denver
- Diseases
- Obesity
- NCT number
- NCT07428187
What you commit to
- Study type: Interventional
- Planned participants: 70
- From 5 Mar 2026 to the primary completion date, 31 Mar 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Taking weight-loss medications, or steroids within \~3 months prior to study participation (e.g., GLP-1 receptor agonists)
- Significant mental health changes within \~3 months prior to study participation (e.g., medication adjustments, new psychiatric diagnoses, hospitalization relating to mental health concerns)
- Weight change greater than 10% within 3 months prior to study participation
Other illness
- Nut or wheat allergy
- History of bariatric surgery
- Current eating disorder
- Uncontrolled hypertension (\>160/100 mmHg)
- Significant endocrine/metabolic disease kidney disease, liver disease, or blood disease that would be anticipated to affect study results
- Taking injectable medications, sulfonylureas, or meglitinides for diabetes treatment
- Neurological illnesses or injury that would be anticipated to affect MRI data
Other
- Current illicit substance use
- Current pregnancy, lactation (or less than 3 months after stopping lactation), or less than 6 months postpartum
- Currently participating in another weight-loss study
- Not comfortable eating the study-provided meals (with allowances for dietary preferences) and/or following a highly restrictive diet (e.g., vegan)
- MRI-specific exclusion criteria (e.g., metal in the body, weight \>500 lbs
Who the study is looking for
- 25-45 years old
- BMI at least 27 kg/m2
- Comfortable completing a weight-loss intervention\\
- Willing to consume a daily snack of either walnuts or pretzels
Age in the registry: 25 years to 45 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Colorado Anschutz Medical Campus Coordinator of this site? Confirm its status | Aurora | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.