NCT07430826Not yet recruiting
Building Opportunities for Nurturing Care to Enhance Child Development in Eastern and Southern Africa
Building Opportunities for Nurturing Care to Enhance Development in Eastern and Southern Africa
Source: ClinicalTrials.gov · Last updated 3 Mar 2026
Brief summary (registry, in English)
The goal of this randomized controlled trial is to adapt and test a package of interventions to provide nurturing care for children aged 0-2 years in three countries (Botswana, Kenya, Zimbabwe). Mothers living with and without HIV will be enrolled in pregnancy, and their children will be followed for two years. The main objectives of this study are to: * Determine whether the adapted package of interventions improves neurodevelopment among children with and without in utero HIV exposure * Identify why the intervention does or does not impact children's neurodevelopment. Researchers will compare children who receive the intervention package and those who do not to see if the interventions improve child neurodevelopment and growth. Researchers will also compare children with and without HIV exposure to see if there are improvements in neurodevelopment and growth for children who were exposed to HIV. All participants will attend regular prenatal and postnatal care appointments. Participants who are randomized to receive the package of interventions will attend regularly scheduled visits where they will discuss problem-solving strategies, receive information on healthy foods for children, and learn about how to play with their children. Mothers receiving the intervention package will also have the opportunity to meet with other mothers and babies in small groups where their children can play together.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 1260 (estimated)
- First submitted
- 17 Feb 2026
- Start date
- Nov 2026
- Primary completion date
- Dec 2029
- Lead sponsor
- University of Washington
- NCT number
- NCT07430826
What you commit to
- Study type: Interventional
- Planned participants: 1260
- From Nov 2026 to the primary completion date, Dec 2029
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Pregnant women and mothers who participated in the Aim 1 pilot of the BONDS interventions or has previously participated in the BONDS interventions during the trial
Other illness
- Pregnant women, mothers, and babies who have any acute or chronic condition which, in the opinion of the study team, means enrollment in the trial would not be advisable
Other
- Incarcerated individuals
- Any pregnant women and mothers who live in a home in which a BONDS participant has already been enrolled
Who the study is looking for
- Pregnant woman attending participating clinics
- ≥15 years of age
- Willing to disclose a known positive HIV status or undergo HIV testing if serostatus is unknown or negative
- Willing to attend follow up visits
- Resides inside of the study catchment area and does not plan to move within the next 2 years
Age in the registry: 15 years to - · Sex: Female · Accepts healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.