NCT07432555Not yet recruiting
Testing a Mobile Health Application to Improve HIV Prevention and Substance Use Treatment Among Women Involved in the Carceral System
Development and Pilot Testing of a Mobile Health Application to Improve HIV Prevention and Substance Use Treatment Service Access Among Women Involved in the Carceral System
Source: ClinicalTrials.gov · Last updated 29 Sept 2026
Brief summary (registry, in English)
Women involved in the carceral system (WICS) are at higher risk for both HIV and substance use than the general public. WICS are also more likely to engage in behaviors both before and after release that put them at risk for HIV and for overdose, due to opioid use. Despite these risk factors, WICS are less likely to be aware of, use, or adhere to pre-exposure prophylaxis (PrEP) and have less access to medications for opioid use disorder (MOUD). The primary goal of the proposed research is to pilot test a systematically developed PrEP and MOUD uptake intervention for WICS using contextually relevant messages developed through novel formative research methods and embedded in a web-based application in a rigorous research design. The investigators will then test this approach (called PA-LINKS) in a pilot randomized trial with women who have recently been incarcerated in Philadelphia in partnership with Philadelphia FIGHT, a federally qualified health center, for promise of efficacy, and to assess feasibility and acceptability.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 74 (estimated)
- First submitted
- 13 Feb 2026
- Start date
- 20 Oct 2026
- Primary completion date
- 30 May 2027
- Lead sponsor
- Temple University
- Diseases
- HIV
- NCT number
- NCT07432555
What you commit to
- Study type: Interventional
- Planned participants: 74
- From 20 Oct 2026 to the primary completion date, 30 May 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Does not have previous experience with the criminal legal system within the last 6 months
- Does not have HIV risk in last six months or six months prior to being incarcerated
- Has not used opioids in past six months or six months prior to being incarcerated or MOUD in last year
Other illness
- Has been diagnosed with HIV
Age
- Under 18 years old
Other
- Does not read or speak English
- Does not identify as a woman
- Does not have access to internet
- Cannot provide informed consent
Who the study is looking for
- 18 of years of age or older
- Self-identified woman
- Previous experience (past six months) with the carceral system (jail, prison, on parole or under supervision)
- Speaks and reads English
- Self-reported negative HIV status
- Indicates at least one HIV risk (i.e. any of the following in the past 6 months or in the six months prior to the most recent incarceration that call for consideration of PrEP as per the CDC risk indices: have engaged in condomless sex; have an HIV-positive sex partner; have had an STI; have had multiple \[\>6\] partners; have engaged in transactional sex; have injected drugs, shared injection or drug use preparation equipment, or have been enrolled in opiate substitution therapy because of IDU; previous overdose)
- Self-report using opioids in the past six months or six months prior to the most recent incarceration (prescription or not) OR self-report using medications for opioid use disorder in the past year.
- Have access to the internet through some device - smart phone, computer or tablet (personal or at community location such as library or organization)
Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Temple University Coordinator of this site? Confirm its status | Philadelphia | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.