NCT07434206Active, not recruitingPhase 2/3
Safety and Efficacy of Dexmedetomidine in Controlling Hemodynamics During Resection of Active Thyroid Secreting Tumors
Safety and Efficacy of Dexmedetomidine in Controlling Hemodynamics During Resection of Active Thyroid Secreting Tumors, A Randomized Multicentric Controlled Clinical Trial
Source: ClinicalTrials.gov · Last updated 25 Feb 2026
Brief summary (registry, in English)
Experienced anesthesiologists often attempt to anticipate and blunt the hypertensive responses seen in varying degrees at critical moments of surgical stimulation. Additionally, it may take a long time to treat acute intraoperative hypertension using anesthetics, and there may be a subsequent period of hypotension due to over-compensation. Most practicing anesthesiologists rely on antihypertensive drugs for the rapid control of elevated arterial blood pressure, when volatile anesthetics and narcotics need to be discontinued for awakening. Relatively high doses of antihypertensive drugs, such as labetalol, nicardipine, or esmolol, are commonly used, regardless of the anesthetic technique.One of the main methods to control arterial blood pressure intraoperatively, was to use a typical antihypertensive regimen on an as-needed basis as well as common methods; adjustments in the concentration of volatile anesthetic.
- Status (registry)
- Active, not recruiting
- Phase (registry)
- Phase 2/3
- Study type
- Interventional
- Enrollment
- 80 (estimated)
- First submitted
- 7 Jun 2024
- Start date
- 25 Apr 2024
- Primary completion date
- 1 Mar 2026
- Lead sponsor
- South Egypt Cancer Institute
- Diseases
- Thyroid cancer
- NCT number
- NCT07434206
What you commit to
- Study type: Interventional · Phase 2/3
- Planned participants: 80
- From 25 Apr 2024 to the primary completion date, 1 Mar 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Allergy to dexmedetomidine
Other
- ASA physical status \>III and NYHA \>II,
- body mass index \>40 kg/m2,
- pregnant women,
- preoperative opioid consumption,
- Contraindications as hypotension or cardiovascular compromise
- Unwilling to participate in the study
Who the study is looking for
- Patients subjected to thyroid resection surgeries for active thyroid tumors.
- The enrolled age will be from 20 years to 65 years
- ASA, I-III and NYHA, I-II.
Age in the registry: 20 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| south Egypt cancer institute Coordinator of this site? Confirm its status | Asyut | Egypt | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.