NCT07434908Recruiting
Heparin-binding Protein and Lungedema in ICU Patients.
Heparin-binding Protein (HBP) and Lungedema in ICU Patients. Is There a Correlation Between HBP and Pulmonary Vascular Permeability? A Prospective Observational Study
Source: ClinicalTrials.gov · Last updated 10 Mar 2026
Brief summary (registry, in English)
The goal of this single center observational cohort study is to investigate the relationship between physiological measures of lung oedema, and the biomarker Heparin-binding Protein (HBP). The main questions it aims to answer are: * Does the concentration of HBP in plasma correlate with measures of lung vascular permeability and extravascular water in the lungs? * Does the concentration of HBP in plasma correlate with the patient's total accumulated fluid balance? Researchers will collect blood samples and gather information on lung vascular permeability and extravascular lung water in Intensive care patients who are provided with a hemodynamic surveillance system called PiCCO. The study will include 25 patients.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 25 (estimated)
- First submitted
- 2 Feb 2026
- Start date
- 6 May 2024
- Primary completion date
- 1 Jul 2026
- Lead sponsor
- Umeå University
- NCT number
- NCT07434908
What you commit to
- Study type: Observational
- Planned participants: 25
- From 6 May 2024 to the primary completion date, 1 Jul 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Patients transferred from another ICU
Who the study is looking for
- Patients \>18 years
- Monitored with a PiCCO system
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| ICU Coordinator of this site? Confirm its status | Östersund | Sweden | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.