Fact CheckerSign in

NCT07434908Recruiting

Heparin-binding Protein and Lungedema in ICU Patients.

Heparin-binding Protein (HBP) and Lungedema in ICU Patients. Is There a Correlation Between HBP and Pulmonary Vascular Permeability? A Prospective Observational Study

Source: ClinicalTrials.gov · Last updated 10 Mar 2026

Brief summary (registry, in English)

The goal of this single center observational cohort study is to investigate the relationship between physiological measures of lung oedema, and the biomarker Heparin-binding Protein (HBP). The main questions it aims to answer are: * Does the concentration of HBP in plasma correlate with measures of lung vascular permeability and extravascular water in the lungs? * Does the concentration of HBP in plasma correlate with the patient's total accumulated fluid balance? Researchers will collect blood samples and gather information on lung vascular permeability and extravascular lung water in Intensive care patients who are provided with a hemodynamic surveillance system called PiCCO. The study will include 25 patients.

Status (registry)
Recruiting
Study type
Observational
Enrollment
25 (estimated)
First submitted
2 Feb 2026
Start date
6 May 2024
Primary completion date
1 Jul 2026
Lead sponsor
Umeå University
NCT number
NCT07434908

What you commit to

  • Study type: Observational
  • Planned participants: 25
  • From 6 May 2024 to the primary completion date, 1 Jul 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • Patients transferred from another ICU

Who the study is looking for

  • Patients \>18 years
  • Monitored with a PiCCO system

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
ICU
Coordinator of this site? Confirm its status
ÖstersundSwedenRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.