NCT07437729Recruiting
Glycocalyx and Oxidative Stress in Endothelial Function (Part 1)
The Role of Glycocalyx and Oxidative Stress in Endothelial Function (Part 1)
Source: ClinicalTrials.gov · Last updated 2 Mar 2026
Brief summary (registry, in English)
The primary research objective of the project is to determine the role of eGC in microvascular reactivity in CKD (cross-sectional study 1). The main objective of the project is to increase the excellence and interdisciplinarity of scientific work at MEFOS by connecting researchers from different scientific fields, improving conditions and resources for scientific work, and increasing international cooperation, in line with strategic objective 1: raising scientific excellence. The results of the project could provide pathophysiological insight into the development and maintenance of endothelial dysfunction in CKD, as well as identify new biomarkers for CKD.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 105 (estimated)
- First submitted
- 16 Feb 2026
- Start date
- 1 Oct 2025
- Primary completion date
- 30 Sept 2029
- Lead sponsor
- Josip Juraj Strossmayer University of Osijek
- Diseases
- Chronic kidney disease
- NCT number
- NCT07437729
What you commit to
- Study type: Observational
- Planned participants: 105
- From 1 Oct 2025 to the primary completion date, 30 Sept 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- kidney disease of any other etiology except hypertension
- endocrine, autoimmune or inflammatory diseases that could affect kidney function.
- diabetes
Other
- smoking
Who the study is looking for
- patients with CKD of hypertensive etiology (grades 1-2 and 3-5; eGFR CKD-EPI GFR ≥ 90 ml/min/1.73 m², i.e. \< 60 mL/min/1.73 m2), non-diabetics, non-smokers
- patients with hypertension (according to ESH2023 Guidelines) without kidney damage (eGFR CKD-EPI \>90 mL/min/1.73 m2) non-diabetics, non-smokers
- healthy volunteer subjects as controls
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Osijek University Hospital Coordinator of this site? Confirm its status | Osijek | Croatia | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.