NCT07438054Enrolling by invitation
PRO-AF 52: Monthly Primary-Care 12-Lead ECG Screening for Incident Atrial Fibrillation in Adults Aged ≥65 Years
A Prospective, Single-Group, Primary-Care-Based 12-Lead ECG Screening Program With 12-Month Follow-up for Incident Atrial Fibrillation and Guideline-Directed Oral Anticoagulation in Ordu, Türkiye (PRO-AF 52)
Source: ClinicalTrials.gov · Last updated 27 Feb 2026
Brief summary (registry, in English)
This prospective, single-arm study will evaluate the feasibility and yield of monthly, in-clinic 12-lead electrocardiogram (ECG) screening performed at affiliated Family Health Centers (Aile Sağlığı Merkezleri; ASMs) in Ordu, Türkiye, among community-dwelling adults aged ≥65 years without a prior diagnosis of atrial fibrillation (AF). Each participant will be followed for 12 months (12 visits). New AF will be confirmed on ASM-acquired 12-lead ECG and managed by the tertiary Cardiology Department according to contemporary guidelines, including initiation of oral anticoagulation (OAC) when indicated. Outcomes include incident AF detection, OAC initiation and adherence, and ischemic/hemorrhagic clinical events.
- Status (registry)
- Enrolling by invitation
- Study type
- Observational
- Enrollment
- 1000 (estimated)
- First submitted
- 22 Feb 2026
- Start date
- 1 Jan 2026
- Primary completion date
- 30 Dec 2027
- Lead sponsor
- Kotyora Family Medicine Health Management and Education Association
- Diseases
- Stroke, Atrial fibrillation
- NCT number
- NCT07438054
What you commit to
- Study type: Observational
- Planned participants: 1000
- From 1 Jan 2026 to the primary completion date, 30 Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior diagnosis of atrial fibrillation or atrial flutter.
Other
- Long-term therapeutic anticoagulation for any indication at baseline.
- Residence in long-term care, hospice, or palliative status.
- Enrollment in another interventional study that conflicts with the protocol.
- Planning to relocate or otherwise unable to attend monthly visits.
Who the study is looking for
- Age ≥65 years.
- Registered at a participating Family Health Center (ASM) in Ordu, Türkiye, with expected availability for 12 months of follow-up.
- Able to provide written informed consent
Age in the registry: 65 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ordu University Faculty of Medicine, Department of Cardiology Coordinator of this site? Confirm its status | Ordu | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.