NCT07438444Active, not recruitingPhase 4
A Study of Tirzepatide (LY3298176) in Adult Participants in India With Either Type 2 Diabetes Mellitus or Obesity
A Phase 4, Open-Label, Single-Arm, 46-Week Study to Investigate the Safety and Efficacy With Tirzepatide in Adult Indian Participants With Either Type 2 Diabetes or Obesity
Source: ClinicalTrials.gov · Last updated 21 Aug 2026
Brief summary (registry, in English)
The main purpose of this study is to measure the safety and efficacy of tirzepatide in adult participants in India who have type 2 diabetes or who have obesity or overweight without type 2 diabetes. Participation in the study will last about 46 weeks.
- Status (registry)
- Active, not recruiting
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 344 (estimated)
- First submitted
- 23 Feb 2026
- Start date
- Feb 2026
- Primary completion date
- Jul 2027
- Lead sponsor
- Eli Lilly and Company
- Diseases
- Obesity, Type 2 diabetes
- NCT number
- NCT07438444
What you commit to
- Study type: Interventional · Phase 4
- Planned participants: 344
- From Feb 2026 to the primary completion date, Jul 2027
- 21 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Have had any of the following heart conditions within 6 months prior to screening:
- heart attack
- stroke
- hospitalization due to heart failure
- Have a self-reported change in body weight greater than 5 kilograms (kg) (11 pounds) within 3 months prior to screening
- Have a prior or planned surgical treatment for obesity
- Have had any of the following heart conditions within 6 months prior to screening:
- heart attack
- stroke
- hospitalization due to heart failure
- Have taken any medications or alternative remedies for weight loss within 3 months prior to screening
Other illness
- Participants with Type 2 Diabetes:
- Have type 1 diabetes
- Have New York Heart Association Functional Classification Class III or IV congestive heart failure (CHF)
- Have type 2 diabetes along with morbid obesity and being considered for bariatric surgery or any other procedure intended for weight loss
- Participants with Obesity or Overweight without Type 2 Diabetes:
- Have type 1 diabetes or type 2 diabetes
- Have New York Heart Association Functional Classification Class III or IV CHF
Who the study is looking for
- Participants with Type 2 Diabetes:
- Have had type 2 diabetes for at least one year
- Insulin naive
- Have HbA1c ≥7.5% and ≤10% at screening
- Have body mass index (BMI) ≥23 kilograms per square meter (kg/m2)
- Participants with Obesity or Overweight without Type 2 Diabetes:
- Have a BMI
- Greater than or equal to 30 kg/m2 OR
- Greater than or equal to 27 kg/m2 AND previously diagnosed with at least one of the following weight-related comorbidities: high blood pressure, lipid disorder, obstructive sleep apnea, heart disease
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (21)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Gujarat Endocrine Center Coordinator of this site? Confirm its status | Ahmedabad | India | Unknown status |
| V.S. General Hospital Coordinator of this site? Confirm its status | Ahmedabad | India | Unknown status |
| B. J. Medical College & Civil Hospital Coordinator of this site? Confirm its status | Ahmedabad | India | Unknown status |
| Jawahar Lal Nehru Medical College Coordinator of this site? Confirm its status | Ajmer | India | Unknown status |
| Motilal Nehru Medical College Hospital Coordinator of this site? Confirm its status | Allahabād | India | Unknown status |
| Lifecare Hospital and Research Centre Coordinator of this site? Confirm its status | Bengaluru | India | Unknown status |
| AIIMS, Bhubaneshwar Coordinator of this site? Confirm its status | Bhubaneswar | India | Unknown status |
| Sri Ramachandra MedicaL College & Research Institute Coordinator of this site? Confirm its status | Chennai | India | Unknown status |
| Kovai Diabetes Speciality Center and Hospital Coordinator of this site? Confirm its status | Coimbatore | India | Unknown status |
| Apollo-Excelcare Hospital Coordinator of this site? Confirm its status | Guwahati | India | Unknown status |
| Osmania Medical College & Hospital Coordinator of this site? Confirm its status | Hyderabad | India | Unknown status |
| Eternal Heart Care Center and Research Institute Coordinator of this site? Confirm its status | Jaipur | India | Unknown status |
| K care Hospital Coordinator of this site? Confirm its status | Kanpur | India | Unknown status |
| Brij Medical Centre Private Limited Coordinator of this site? Confirm its status | Kanpur | India | Unknown status |
| ILS Hospitals Coordinator of this site? Confirm its status | Kolkata | India | Unknown status |
| Government Medical College, Kozhikode Coordinator of this site? Confirm its status | Kozhikode | India | Unknown status |
| Wockhardt Hospitals Coordinator of this site? Confirm its status | Mumbai | India | Unknown status |
| Shri Krishna Hrudayalaya & Critical Care Centre Coordinator of this site? Confirm its status | Nagpur | India | Unknown status |
| Sahyadri Super Speciality Hospital Coordinator of this site? Confirm its status | Pune | India | Unknown status |
| All India Institute of Medical Sciences Coordinator of this site? Confirm its status | Raipur | India | Unknown status |
| King George Hospital, Andhra Medical College Coordinator of this site? Confirm its status | Visakhapatnam | India | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.