NCT07440563Enrolling by invitation
Auricular Vagus Nerve Stimulation Combined With Rehabilitation in Parkinson's Disease
Investigation of the Effects of Auricular Vagus Nerve Stimulation Combined With Neurological Physiotherapy and Rehabilitation on Balance, Gait, and Clinical Symptoms in People With Parkinson's Disease
Source: ClinicalTrials.gov · Last updated 5 Mar 2026
Brief summary (registry, in English)
Parkinson's disease (PD) is a progressive, neurodegenerative movement disorder characterized by a combination of motor and non-motor symptoms. Auricular vagus nerve stimulation (aVNS), one of the physiotherapy methods used in PD, has been shown in studies to have a positive effect on symptoms such as motor symptoms, gait disturbance, freezing, and cognitive impairment, and is considered a safe and feasible method. The aim of this study is to investigate the effects of neurological physiotherapy and rehabilitation, in combination with aVNS application, on balance, gait, and clinical symptoms in individuals with PD.
- Status (registry)
- Enrolling by invitation
- Study type
- Interventional
- Enrollment
- 20 (estimated)
- First submitted
- 16 Feb 2026
- Start date
- 3 Mar 2026
- Primary completion date
- 23 Mar 2027
- Lead sponsor
- Gazi University
- Diseases
- Parkinson disease
- NCT number
- NCT07440563
What you commit to
- Study type: Interventional
- Planned participants: 20
- From 3 Mar 2026 to the primary completion date, 23 Mar 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Presence of metallic implants in the head or neck region
Other illness
- Presence of additional neurological (e.g., migraine), orthopedic (e.g., osteoarthritis), or cardiovascular conditions (e.g., myocardial infarction, uncontrolled hypertension, arrhythmias)
- Presence of a cardiac pacemaker
- History of deep brain stimulation surgery
Other
- Score below 21 on the Montreal Cognitive Assessment (MoCA)
- Presence of uncorrected visual or hearing impairments
Who the study is looking for
- Diagnosis of Parkinson's disease confirmed by a neurologist according to the United Kingdom Brain Bank criteria
- Age 40 years or older
- Hoehn and Yahr stage between 1 and 3 according to the Modified Hoehn and Yahr Staging Scale
- Stable pharmacological treatment regimen
- Ability to turn 180 degrees and walk 30 meters independently without assistance
Age in the registry: 40 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Gazi University Coordinator of this site? Confirm its status | Ankara | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.