NCT07441304Completed
Cardiometabolic Risk Factor Management and Adherence to Antihypertensive Therapy in Patients With Severe Obesity Prior to Bariatric Surgery: a Prospective Longitudinal Cohort Study
Source: ClinicalTrials.gov · Last updated 27 Feb 2026
Brief summary (registry, in English)
Patients with severe obesity frequently exhibit elevated cardiovascular risk. Contributing factors could be inadequate recognition and subsequent management of cardiovascular risk factors, and non-adherence to cardiovascular therapy. This prospective longitudinal cohort study aims to systematically assess the management of major cardiovascular risk factors and objectively evaluate adherence to antihypertensive therapy in patients with severe obesity undergoing evaluation for bariatric surgery. Using repeated assessments and direct plasma drug detection, the study seeks to characterise adherence patterns over time and identify clinical factors associated with persistent non-adherence.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 80 (actual)
- First submitted
- 29 Jan 2026
- Start date
- 4 Aug 2022
- Primary completion date
- 26 Nov 2024
- Lead sponsor
- Universität des Saarlandes
- Diseases
- Obesity
- NCT number
- NCT07441304
What you commit to
- Study type: Observational
- Participants enrolled: 80
- From 4 Aug 2022 to the primary completion date, 26 Nov 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Absence of arterial hypertension
Other
- No current antihypertensive pharmacotherapy
- Inability to provide informed consent
- Pregnancy
Who the study is looking for
- Age ≥18 years
- Severe obesity with an indication for bariatric surgery (body mass index ≥40 kg/m², or body mass index ≥35 kg/m² with obesity-associated cardiovascular risk factors)
- Documented diagnosis of arterial hypertension
- Ongoing pharmacological antihypertensive therapy at the time of screening
- Ability to provide written informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Universitätsklinikum des Saarlandes Coordinator of this site? Confirm its status | Homburg | Germany | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.