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NCT07443345Recruiting

Incidence of Postoperative Diaphragmatic Dysfunction in Pregnant Women With Preeclampsia

Incidence of Postoperative Diaphragmatic Dysfunction in Pregnant Women With Preeclampsia With Severe Features Undergoing Cesarean Delivery: A Prospective Observational Study

Source: ClinicalTrials.gov · Last updated 11 Mar 2026

Brief summary (registry, in English)

Preeclampsia with severe features remains a leading contributor to maternal morbidity and mortality, particularly in low- and middle-income countries. It is defined by hypertension and involvement of multiple organ systems, including renal, hepatic, hematologic, and neurologic pathways. The interplay of endothelial dysfunction, capillary leakage, and disrupted fluid balance in these patients increases their susceptibility to perioperative pulmonary complications. Although respiratory complications in preeclampsia are clinically significant, the true incidence of postoperative diaphragmatic dysfunction in women with severe disease is not well established. Existing literature largely emphasizes general respiratory failure, pulmonary edema, or the need for mechanical ventilation, rather than specifically evaluating diaphragmatic performance with objective methods such as ultrasound. The current study sought to determine the incidence and identify risk factors for postoperative diaphragmatic dysfunction in women with severe preeclampsia following cesarean delivery.

Status (registry)
Recruiting
Study type
Observational
Enrollment
52 (estimated)
First submitted
25 Feb 2026
Start date
9 Mar 2026
Primary completion date
30 Dec 2026
Lead sponsor
Cairo University
NCT number
NCT07443345

What you commit to

  • Study type: Observational
  • Planned participants: 52
  • From 9 Mar 2026 to the primary completion date, 30 Dec 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Lab values

  • • Age \< 20 years.
    • Diabetic
    • Patients with neuromuscular diseases.
    • Patient refusal.
    • Contraindications to magnesium sulphate administration
    • Inability to obtain adequate ultrasound views

Who the study is looking for

  • Patients with severe preeclampsia undergoing cesarean section
  • Gestational age \> 32 weeks

Age in the registry: 20 years to 40 years · Sex: Female · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Cairo University Hospitals
Coordinator of this site? Confirm its status
CairoEgyptRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.