NCT07446296Recruiting
Kidney Transplant Improvement Through New Exercise Training to Increase Capacity
KINETIC -- Kidney Transplant Improvement Through New Exercise Training to Increase Capacity
Source: ClinicalTrials.gov · Last updated 6 May 2026
Brief summary (registry, in English)
The goal of this clinical trial is to learn if a home-based exercise program can be safely and feasibly used to improve physical activity and physical function in adults waiting for a kidney transplant. The study will also learn how acceptable and useful this program is for participants. The main questions it aims to answer are: * Can a remote exercise program be delivered successfully to people on the kidney transplant waiting list? * Do participants follow the exercise program and wear a physical activity tracker as asked? * Is the program safe and well tolerated? Researchers will compare two groups to see if the exercise program leads to higher physical activity and better physical function: * Usual pre-transplant care with a physical activity tracker * Usual pre-transplant care plus an online exercise program Participants will: * Wear a wrist activity tracker to measure daily physical activity * Complete a one-week baseline period before being assigned to a study group * Be randomly assigned (like flipping a coin) to one of two groups * If assigned to the exercise group, take part in online exercise classes at home for 12 weeks with reminders and feedback, and then another 12 weeks without reminders and feedback * Answer questionnaires about their health, activity, and experience in the study This study may help researchers learn how to better support people waiting for kidney transplant through safe, home-based exercise programs.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 28 Jan 2026
- Start date
- 24 Mar 2026
- Primary completion date
- 31 Mar 2028
- Lead sponsor
- University of Pennsylvania
- Diseases
- Chronic kidney disease
- NCT number
- NCT07446296
What you commit to
- Study type: Interventional
- Planned participants: 60
- From 24 Mar 2026 to the primary completion date, 31 Mar 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Have had a myocardial infarction or a stroke in the 3 months immediately prior to enrollment
Other illness
- Be unable to self-monitor with study devices (i.e., have a condition such as dementia)
Lab values
- Not cleared by PARQ or receive written medical clearance to exercise
Other
- Participate in another physical activity study
- Have any other reason they do not expect to be able to complete the study
Who the study is looking for
- be at least 60 years old
- receive transplant care at Penn Medicine
- be on the kidney transplant waiting list
- speak and comprehend English
- be able to walk
- have at least one physical function limitation OR at least one frailty metric
- have access to a device capable of connecting to the Internet and downloading an application
- be able to provide written informed consent
- be cleared for participant via the Physical Activity Readiness Questionnaire (PARQ) verified against medical record or via written medical clearance from a clinician
Age in the registry: 60 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Perelman Center for Advanced Medicine Coordinator of this site? Confirm its status | Philadelphia | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.