NCT07447414Recruiting
Luminal Breast Cancer Cryoablation
Cryoablation for the Treatment of Luminal Early Breast Cancer
Source: ClinicalTrials.gov · Last updated 16 Apr 2026
Brief summary (registry, in English)
LUBRECA will evaluate the safety and efficacy of cryoablation with liquid nitrogen to treat cT1cN0 luminal breast cancer diagnosed in postmenopausal women
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 140 (estimated)
- First submitted
- 23 Feb 2026
- Start date
- 8 Apr 2026
- Primary completion date
- Sept 2028
- Lead sponsor
- Lucía Graña López
- Diseases
- Childhood cancers
- NCT number
- NCT07447414
What you commit to
- Study type: Interventional
- Planned participants: 140
- From 8 Apr 2026 to the primary completion date, Sept 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Not candidate for surgery
Other
- Infiltrating lobular carcinoma
- Extensive in situ component
- Multifocality or multicentricity
- Contraindication for contrast mammography
- Distant metastasis -
Who the study is looking for
- Postmenopausal women diagnosed with invasive breast cancer by core needle biopsy or vacuum-assisted biopsy
- Unifocal
- Lesion ≤ 2 cm (on ultrasound and contrast enhanced mammography)
- No axillary lymphadenopathy on ultrasound
- No axillary lymph node involvement on ultrasound.
- Luminal tumor (estrogen and/or progesterone receptor positive)
- HER2 negative
- Signed informed consent
Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hospital Universitario Lucus Augusti Coordinator of this site? Confirm its status | Lugo | Spain | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.