NCT07447908Recruiting
Ted Rogers Understanding of Exacerbations in Heart Failure 2: Monitor
Ted Rogers Understanding of Exacerbations in Heart Failure 2 (TRUE-HF2): Observational Study
Source: ClinicalTrials.gov · Last updated 6 Jul 2026
Brief summary (registry, in English)
Heart Failure (HF) is a complex disease associated with the highest burden of cost to the healthcare system. The cardiopulmonary exercise test (CPET) is instrumental in determining the prognosis of patients with HF. This multicentre study will validate whether aggregate biometric data from the Apple Watch combined with demographic, cardiac, and biomarker testing can improve our ability to predict heart failure outcomes among a diverse outpatient HF population.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 360 (estimated)
- First submitted
- 25 Feb 2026
- Start date
- 16 Jun 2026
- Primary completion date
- 30 Sept 2029
- Lead sponsor
- University Health Network, Toronto
- Diseases
- Heart failure
- NCT number
- NCT07447908
What you commit to
- Study type: Observational
- Planned participants: 360
- From 16 Jun 2026 to the primary completion date, 30 Sept 2029
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- End stage renal disease requiring dialysis
- Post heart transplant
Other
- Unable to perform a CPET based on the standard protocol
- Living with LVAD
- MRP deems patient unfit for the study
Who the study is looking for
- broad age range (\> 18 years of age)
- NT-proBNP \> 400 or 1000 if in AF
- Within 3 months post discharge from HF hospitalization/ HF ED visit/ HF rapid clinic visit with intensification of diuretic therapy
- NYHA functional class I-IV, heart failure with reduced and preserved ejection fraction
- Literacy in English
- Patient provided informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Southlake Health Coordinator of this site? Confirm its status | Newmarket | Canada | Not yet recruiting |
| 200 Elizabeth Street Coordinator of this site? Confirm its status | Toronto | Canada | Recruiting |
| Sunnybrook Health Sciences Center Coordinator of this site? Confirm its status | Toronto | Canada | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.