NCT07449117Recruiting
Effect of Striatal Temporal Interference Stimulation on Language Processing in Neurodegenerative Diseases
Immediate Effects of Non-invasive Temporal Interference Stimulation Targeting Deep Fronto-Striatal Structures on Language Processing and Behavioral Performance in Patients With Neurodegenerative Diseases
Source: ClinicalTrials.gov · Last updated 4 Mar 2026
Brief summary (registry, in English)
The purpose of this study is to investigate the immediate effects of non-invasive temporal interference stimulation (TIS) targeting the striatum on sentence processing and brain connectivity in patients with neurodegenerative diseases.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 70 (estimated)
- First submitted
- 27 Feb 2026
- Start date
- 1 Mar 2026
- Primary completion date
- 31 Dec 2027
- Lead sponsor
- Masaryk University
- Diseases
- Lewy body dementia, Parkinson disease
- NCT number
- NCT07449117
What you commit to
- Study type: Interventional
- Planned participants: 70
- From 1 Mar 2026 to the primary completion date, 31 Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Any severe psychiatric disorder.
- History of other neurological diseases affecting the central nervous system.
- Uncompensated internal or oncological disease.
Other
- Severe head trauma.
- Presence of MRI-incompatible metal in the body (e.g., pacemaker).
Who the study is looking for
- Possible or probable Mild Cognitive Impairment with Lewy Bodies (MCI-LB), in Parkinson's Disease (MCI-PD) or Amnestic Mild Cognitive Impairment (aMCI).
Age in the registry: 60 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CEITEC MU (Central European Institute of Technology, Masaryk University) Coordinator of this site? Confirm its status | Brno | Czechia | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.