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NCT07449520Not yet recruiting

Endoscopic Sleeve Gastroplasty (ESG) Prospective Trial for Obesity (EGO-Trial)

Endoscopic Sleeve Gastroplasty (ESG) Prospective Trial for Obesity

Source: ClinicalTrials.gov · Last updated 4 Mar 2026

Brief summary (registry, in English)

EGO-Trial is the first multicenter study in France which aims to evaluate the efficacy of Endoscopic Sleeve Gastroplasty (ESG) in patients with obesity. This project fills a critical national gap by providing real-world, multicentric data from diverse French healthcare settings, offering insight into the safety, efficacy, and variability of ESG practices across institutions The project is expected to generate robust, multicentric clinical evidence on the safety and efficacy of ESG in patients with obesity within the French healthcare context.

Status (registry)
Not yet recruiting
Study type
Observational
Enrollment
300 (estimated)
First submitted
27 Feb 2026
Start date
Mar 2026
Primary completion date
Mar 2030
Lead sponsor
IHU Strasbourg
Diseases
Obesity
NCT number
NCT07449520

What you commit to

  • Study type: Observational
  • Planned participants: 300
  • From Mar 2026 to the primary completion date, Mar 2030
  • 10 sites in 2 countries
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Patients who have started medication in the last 3 months that is known to cause weight gain.
  • Patients who are currently excluded (as determined by a previous or ongoing study).

Other illness

  • Patients with active peptic ulcer disease or significant gastroparesis
  • Patients with a history of bariatric, gastric, or esophageal surgery.
  • Patients with a history of uncontrolled, poorly controlled, or suspected eating disorders or psychiatric illness.

Age

  • Patients who are pregnant, breastfeeding, or of childbearing age and not using effective contraception.

Other

  • Patients with contraindications to endoscopic gastroplasty
  • Patients with unstable and precarious health, as determined and assessed by the investigator.
  • Patients under judicial protection.
  • Patients under guardianship, conservatorship or subject to any form of protective supervision

Who the study is looking for

  • Patients aged 18 to 75 years.
  • Patients with a Body Mass Index (BMI) ≥ 30 kg/m².
  • Patients who have failed non-surgical weight loss interventions (diet, exercise, pharmacological therapy).
  • Patients not eligible for bariatric surgery or does not wish to undergo it.
  • Patients who can undergo general anesthesia.
  • Patients who are able to participate in all aspects of the study and agree to comply with all study requirements for the entire duration of the study.
  • Patients who are able to fully understand the study and are willing to give their consent to participate in the study.
  • Patients affiliated with the French social security system.

Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (10)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Hopital Prive de Provence
Coordinator of this site? Confirm its status
Aix-en-ProvenceFranceUnknown status
Polyclinique de Franche Comté
Coordinator of this site? Confirm its status
BesançonFranceUnknown status
Clnique des Cèdres
Coordinator of this site? Confirm its status
ÉchirollesFranceUnknown status
Hopital Huriez
Coordinator of this site? Confirm its status
LilleFranceUnknown status
Hospices Civils de Lyon - Hôpital Edourard HERRIOT
Coordinator of this site? Confirm its status
LyonFranceUnknown status
Clinique Clementville
Coordinator of this site? Confirm its status
MontpellierFranceUnknown status
Centre Mutualiste de l'Obésité
Coordinator of this site? Confirm its status
Saint-EtienneFranceUnknown status
Polyclinique Sainte Thérèse
Coordinator of this site? Confirm its status
SèteFranceUnknown status
Hopitaux Universitaires de Strasbourg - Nouvel Hopital Civil
Coordinator of this site? Confirm its status
StrasbourgFranceUnknown status
Clinique les Eaux Claires
Coordinator of this site? Confirm its status
Baie-MahaultGuadeloupeUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.