NCT07450495Completed
Effect of Different Concentrations of Sevoflurane for Anesthesia Induction in Pediatric Ophthalmic Surgery
Effectiveness and Safety of 6% Versus 8% Sevoflurane for Anesthesia Induction in Pediatric Ophthalmic Minor Surgery: A Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 25 Aug 2026
Brief summary (registry, in English)
This randomized controlled trial aims to compare the effectiveness and safety of 6% versus 8% sevoflurane inhalation induction in pediatric patients undergoing minor ophthalmic surgery. The primary outcome is emergence agitation assessed using the Pediatric Anesthesia Emergence Delirium (PAED) scale. Secondary outcomes include hemodynamic parameters, induction time, recovery time, and adverse events.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 80 (actual)
- First submitted
- 23 Feb 2026
- Start date
- Feb 2025
- Primary completion date
- Feb 2026
- Lead sponsor
- Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong
- NCT number
- NCT07450495
What you commit to
- Study type: Interventional
- Participants enrolled: 80
- From Feb 2025 to the primary completion date, Feb 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Congenital heart disease
- History of malignant hyperthermia
- Known allergy to sevoflurane
- History of asthma or severe respiratory disease
- Upper respiratory tract infection within the past 4 weeks
Other
- ASA physical status II or higher
- Known hepatic or renal dysfunction
- Anticipated difficult airway
- Refusal of participation by parents or legal guardians
Who the study is looking for
- Children aged 1 to 6 years (12-72 months)
- Scheduled to undergo minor ophthalmic surgery (e.g., chalazion excision) under general anesthesia
- American Society of Anesthesiologists (ASA) physical status I
- Assessed as suitable for inhalation anesthesia by anesthesiologists
- Written informed consent obtained from parents or legal guardians
Age in the registry: 1 year to 6 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Joint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong Coordinator of this site? Confirm its status | Shantou | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.