NCT07451015Completed
Preoperative Carbohydrate Loading in Diabetic Patients Undergoing Elective Abdominal Surgery
"A Randomized Controlled Trial on the Effect of Preoperative Carbohydrate Loading in Diabetic and Non-Diabetic Patients Undergoing Elective Abdominal Surgery"
Source: ClinicalTrials.gov · Last updated 9 Mar 2026
Brief summary (registry, in English)
This study evaluates the effect of preoperative carbohydrate loading on early postoperative recovery in patients with type 2 diabetes mellitus undergoing elective abdominal surgery. Traditionally, patients fast before surgery, which can increase insulin resistance, delay recovery, and worsen postoperative outcomes. Preoperative carbohydrate drinks may reduce surgical stress and improve recovery, but concerns exist regarding blood glucose control and gastric emptying in diabetic patients. In this randomized, double-blind clinical trial, 120 eligible patients will be assigned to three groups: nondiabetic control, nondiabetic with carbohydrate load, and diabetic with carbohydrate load. Patients will receive either a carbohydrate-rich drink or control solution before surgery. Preoperative gastric residual volume will be measured using ultrasound to assess aspiration risk. Blood glucose levels will be measured before and after carbohydrate intake. Postoperative outcomes including metabolic and inflammatory response, nausea and vomiting, length of hospital stay, and time to independent ambulation will be recorded. The study aims to determine whether preoperative carbohydrate loading is safe and beneficial for diabetic patients undergoing elective abdominal surgery.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 120 (actual)
- First submitted
- 27 Feb 2026
- Start date
- 1 Jun 2024
- Primary completion date
- 1 Jun 2025
- Lead sponsor
- Tanta University
- Diseases
- Type 2 diabetes
- NCT number
- NCT07451015
What you commit to
- Study type: Interventional
- Participants enrolled: 120
- From 1 Jun 2024 to the primary completion date, 1 Jun 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior upper gastrointestinal surgery
- Use of medications affecting gastric motility
- Type 2 diabetes mellitus treated with insulin
Other illness
- Mental dysfunction or cognitive disorders impairing consent or cooperation
- Type 1 diabetes mellitus
Other
- Patient refusal
- Known liver or renal pathology affecting gastric function
- Increased risk of gastric content aspiration
- Body mass index (BMI) \< 20 or \> 35 kg/m²
- Patients with clinical evidence of diabetic gastropathy or autonomic dysfunction
Who the study is looking for
- Adults aged 21-65 years
- Both males and females
- American Society of Anesthesiologists (ASA) physical status I-II
- Scheduled for elective abdominal surgery under general anesthesia
- Able and willing to provide informed consent
Age in the registry: 21 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Tanta University Hospitals Coordinator of this site? Confirm its status | Tanta | Egypt | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.