NCT07451873Recruiting
Glycocalyx and Oxidative Stress in Endothelial Function (Part 2)
The Role of Glycocalyx and Oxidative Stress in Endothelial Function (Part 2)
Source: ClinicalTrials.gov · Last updated 9 Mar 2026
Brief summary (registry, in English)
The primary research objective of the project is to determine the role of eGC in microvascular reactivity in patients with coronary heart disease (CHD) before and after bypass grafting (cross-sectional study 2).The main objective of the project is to increase the excellence and interdisciplinarity of scientific work at MEFOS by connecting researchers from different scientific fields, improving conditions and resources for scientific work, and increasing international cooperation, in line with strategic objective 1: raising scientific excellence. The results of the project could provide pathophysiological insight into the development and maintenance of endothelial dysfunction in CVD, as well as identify new biomarkers for CVD.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 35 (estimated)
- First submitted
- 17 Feb 2026
- Start date
- 1 Oct 2025
- Primary completion date
- 30 Sept 2029
- Lead sponsor
- Josip Juraj Strossmayer University of Osijek
- Diseases
- Coronary artery disease
- NCT number
- NCT07451873
What you commit to
- Study type: Observational
- Planned participants: 35
- From 1 Oct 2025 to the primary completion date, 30 Sept 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- emergency surgery
- sepsis or severe systemic inflammation before surgery
- therapies that could affect oxidative stress (e.g., high doses of corticosteroids)
Other illness
- severe renal or hepatic insufficiency
- serious comorbidities (e.g., active cancer)
Other
- immunosuppression
Who the study is looking for
- adult patients of both sexes over 18 years of age
- Caucasian
- undergoing elective coronary artery bypass grafting (CABG)
- provided written informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Osijek University Hospital Coordinator of this site? Confirm its status | Osijek | Croatia | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.