NCT07454954Not yet recruiting
The Effect of Blood Flow Restriction Training Combined With Transcranial Magnetic Stimulation on Limb Function in Hemiplegic Patients After Stroke
Source: ClinicalTrials.gov · Last updated 6 Mar 2026
Brief summary (registry, in English)
This randomized controlled trial aims to evaluate whether combining blood flow restriction training (BFRT) with repetitive transcranial magnetic stimulation (rTMS) improves limb function in stroke patients with hemiplegia. A total of 69 participants will be randomly assigned to three groups: conventional rehabilitation alone (control group), conventional rehabilitation plus rTMS, or conventional rehabilitation plus BFRT combined with rTMS. The intervention period is 4 weeks, with assessments conducted at baseline and at the end of treatment. The primary outcome is the change in upper extremity Fugl-Meyer Assessment (FMA-UE) score, which measures motor function recovery. Secondary outcomes include Wolf Motor Function Test, Modified Barthel Index for daily activities, Berg Balance Scale, and safety parameters such as coagulation markers and adverse events. This study will help determine whether this combined approach offers a more effective rehabilitation strategy for stroke survivors.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 69 (estimated)
- First submitted
- 23 Feb 2026
- Start date
- 1 Mar 2026
- Primary completion date
- 1 Sept 2026
- Lead sponsor
- The First Affiliated Hospital of Zhengzhou University
- Diseases
- Stroke
- NCT number
- NCT07454954
What you commit to
- Study type: Interventional
- Planned participants: 69
- From 1 Mar 2026 to the primary completion date, 1 Sept 2026
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Presence of cardiac pacemaker or other metal implants
- Deafness, severe cognitive impairment, history of psychiatric disorders
- Severe cardiac, hepatic, pulmonary, or renal insufficiency
- Coagulation disorders
- Post-stroke epilepsy
- Malignancy
Other
- Shoulder subluxation
- Extensive skin damage on affected limbs
- Pregnancy or lactation
Who the study is looking for
- Diagnosis of stroke (ischemic or hemorrhagic) confirmed by CT or MRI, meeting the diagnostic criteria of the 4th National Cerebrovascular Disease Conference
- First-ever stroke or recurrent stroke without residual dysfunction from prior events
- Age 25-70 years, male or female
- Stable vital signs, conscious, able to understand and follow therapist instructions
- Brunnstrom stage III or above in both upper and lower limbs
- Voluntary signed informed consent by patient or legal guardian
Age in the registry: 25 years to 70 years · Sex: All · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.