Sign in

NCT07456475Active, not recruiting

Metaverse Applications in Clinical Neurorehabiliation: Device Feasibility

Tele-Rehabilitation Solutions With Innovative Cores of Extended Reality Based on Metaverse

Source: ClinicalTrials.gov · Last updated 6 Mar 2026

Brief summary (registry, in English)

The main objective of the TERSICORE project is the development of a new advanced set of exergames in the Metaverse that can be used in all clinical and home rehabilitation devices to improve the cognitive therapy of neurological patients by exploiting the potential of social rehabilitation. Five specific exargames will be developed: a) Cooking therapy (Coordinating in a kitchen to complete a dish through shared activities); b) Escape Room (Exiting a simulated room by solving problems and logic puzzles); c) Nostalgia Bits (Sharing personal reminiscence narratives within simulated spaces); d) NeuroTeam (Mindfulness); and e) Truman Show Exploration of an urban space and role-playing. All exargames will be validated on a small population of neurological patients according to cognitive profile.

Status (registry)
Active, not recruiting
Study type
Interventional
Enrollment
25 (estimated)
First submitted
13 Feb 2026
Start date
6 Jun 2025
Primary completion date
1 Apr 2027
Lead sponsor
Istituto per la Ricerca e l'Innovazione Biomedica
NCT number
NCT07456475

What you commit to

  • Study type: Interventional
  • Planned participants: 25
  • From 6 Jun 2025 to the primary completion date, 1 Apr 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Severe cognitive impairment MMSE \<22
  • Presence of major psychiatric or neurological pathologies other than the inclusion criteria

Other

  • Presence of severe deficits in visual acuity, hearing perception, communication and severe dysmetria, such as to interfere with the administration of the activities proposed by TERSICORE

Who the study is looking for

  • Adult age: 18-85 years
  • Education: at least 5 years
  • Cognitive deficits at routine outpatient clinical neuropsychological assessment (at least one test with p.e. 0/1) in subjects with focal neurological insult - (post-Stroke, post-Cranial Trauma)
  • neurodegenerative disorders - (Multiple Sclerosis, Parkinson's, Mild Cognitive Impairment, AD-like)

Age in the registry: 18 years to 85 years · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Save your city in your profile to sort them by distance.

SiteCityCountrySite status
Fondazione Don Gnocchi
Coordinator of this site? Confirm its status
MilanItalyUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.