NCT07457073Active, not recruiting
AI-Powered Sound Analysis for COPD Screening
Clinical Application Study of Chronic Obstructive Pulmonary Disease Screening Using Artificial Intelligence-Based Acoustic Features
Source: ClinicalTrials.gov · Last updated 25 Mar 2026
Brief summary (registry, in English)
Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of morbidity and mortality worldwide, yet early detection remains challenging-especially in primary care settings where spirometry, the diagnostic gold standard, is often unavailable. This study aims to develop and validate a non-invasive, low-cost COPD screening tool based on artificial intelligence (AI) analysis of cough sounds. Using smartphone-recorded cough audio and clinical data from both COPD patients and non-COPD controls, the investigators will train and test an AI model to identify acoustic signatures associated with COPD. The model will be developed using a prospective cohort from Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, and externally validated in a community-based cohort across nine districts/counties in Zhejiang Province, China.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 3000 (estimated)
- First submitted
- 3 Mar 2026
- Start date
- 23 Feb 2026
- Primary completion date
- 1 Feb 2027
- Lead sponsor
- Sir Run Run Shaw Hospital
- Diseases
- COPD
- NCT number
- NCT07457073
What you commit to
- Study type: Observational
- Planned participants: 3000
- From 23 Feb 2026 to the primary completion date, 1 Feb 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Unstable angina or severe arrhythmia
- Severe fatigue due to advanced heart failure or chemotherapy
- Progressive neuromuscular disease
- Other vulnerable populations (e.g., active psychiatric illness, cognitive impairment, critically ill)-except elderly/illiterate individuals who are protected via consent safeguards
Other
- Pregnancy or lactation
- Life expectancy \<6 months
- Unable to complete spirometry or study procedures
Who the study is looking for
- Age ≥18 years
- Diagnosed with COPD per GOLD 2024 criteria OR clinically confirmed as non-COPD （for COPD cohort）
- Able to perform a voluntary cough on instruction
- Provides informed consent (or through legally authorized representative/witness if illiterate)
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Sir Run Run Shaw Hospital Zhejiang University Coordinator of this site? Confirm its status | Hangzhou | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.