NCT07458750Active, not recruiting
Neuromuscular Electrical Stimulation and Voluntary Muscle Contraction in Chronic Hemiplegic Stroke Patients
Source: ClinicalTrials.gov · Last updated 15 Jul 2026
Brief summary (registry, in English)
This single-blinded randomized controlled trial will be conducted at the Physical Therapy Department of the University of Lahore Teaching Hospital after approval from the Institute Research Ethics Board. Eligible participants will be recruited and randomly allocated into two groups by lottery method: Group A (control group) receiving conventional physical therapy, and Group B (experimental group) receiving neuromuscular electrical stimulation (NEMS) combined with voluntary muscle contraction. NEMS will be applied to the tibialis anterior, extensor hallucis longus, and extensor digitorum longus with standard stimulation parameters, while participants perform active dorsiflexion during stimulation. The assessor will remain blinded to group allocation. Outcome measures including spasticity (Modified Ashworth Scale), active range of motion (goniometer), and muscle strength (manual muscle testing) will be evaluated at baseline, 6 weeks, and 12 weeks.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 25 (estimated)
- First submitted
- 4 Mar 2026
- Start date
- 10 Feb 2025
- Primary completion date
- 30 Aug 2026
- Lead sponsor
- University of Lahore
- Diseases
- Stroke
- NCT number
- NCT07458750
What you commit to
- Study type: Interventional
- Planned participants: 25
- From 10 Feb 2025 to the primary completion date, 30 Aug 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Skeletal disorders that hinder the ability of the limb
- Pacemaker or any condition which may lead to a contraindication with NMES
- Patients with any cognitive impairment (MMSE \< 24)
Other
- Parkinson's or multiple sclerosis affecting the nervous systems of the body
- Spasticity (MAS ≥ 3)
- Current botulinum toxin injections in the lower limb that developed the spasticity
Who the study is looking for
- Age of between 43 to 83 years of age
- Diagnosed with chronic stroke (≥6 months in duration) with motor deficits resulting in hemiplegia
- Mild ankle dorsiflexion possible
- MAS score of ≤3 for dorsiflexors to the ankle joint
- Be self-mobility either with or without aids .
Age in the registry: 43 years to 83 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of lahore teaching hospital Coordinator of this site? Confirm its status | Lahore | Pakistan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.