NCT07460882Recruiting
The Impact of Low Sodium Salt Substitute Use on Serum Potassium Levels Among Patients With Hypertension
Source: ClinicalTrials.gov · Last updated 21 Aug 2026
Brief summary (registry, in English)
The goal of this pre-post study is to assess the risk of hyperkalemia in adults with hypertension on medication in Bangladesh. The main questions it aims to answer are: Is the risk of hyperkalemia after the initiation of Low Sodium Salt Substitute (LSSS) in people on antihypertensive medication (especially RASi) large enough to be concerned about its broad use in this population? Does initiation of LSSS correct hypokalemia in people on antihypertensive medication (especially RASi) with low serum potassium levels? Participants will be asked to reduce overall salt intake and to use LSSS on every occasion where regular salt would normally be used, including as cooking salt.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 607 (estimated)
- First submitted
- 5 Mar 2026
- Start date
- 8 Aug 2026
- Primary completion date
- 31 Mar 2027
- Lead sponsor
- Johns Hopkins University
- Diseases
- High blood pressure
- NCT number
- NCT07460882
What you commit to
- Study type: Interventional
- Planned participants: 607
- From 8 Aug 2026 to the primary completion date, 31 Mar 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Other medical conditions determined by physicians (e.g., heart failure treated with medication; life expectancy less than 12 months)
Lab values
- Those with baseline K ≥5.0 or K \<3.0 mmol/L
- Advanced kidney disease (eGFR \<45 ml/min/1.73m2).
- Those on potassium sparing diuretics (e.g., spironolactone)
Other
- Dine out for dinner more than 3 times a week
Who the study is looking for
- Adults ≥18 years with clinically diagnosed hypertension treated with medication \[on a stable dose at least for 2 months\]
- Have a phone for contact
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The National Heart Foundation of Bangladesh Coordinator of this site? Confirm its status | Dhaka | Bangladesh | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.