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NCT07461090Recruiting

Laparoscopic Versus Open Nephrectomy : Clinical Effectivness and Cost Analysis

Source: ClinicalTrials.gov · Last updated 11 Mar 2026

Brief summary (registry, in English)

To evaluate and compare clinical effectiveness (operative time, blood loss, hospital stay, complications and etc) and cost analysis' between laparoscopic nephrectomy and open nephrectomy .

Status (registry)
Recruiting
Study type
Interventional
Enrollment
60 (estimated)
First submitted
19 Feb 2026
Start date
Feb 2026
Primary completion date
Jan 2027
Lead sponsor
Menoufia University
NCT number
NCT07461090

What you commit to

  • Study type: Interventional
  • Planned participants: 60
  • From Feb 2026 to the primary completion date, Jan 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • emergency surgery, dialysis-dependent patients, planned hybrid procedures.
  • Prior extensive ipsilateral retroperitoneal surgery or severe adhesions precluding Laparoscopy.
  • Need for concomitant major procedures (eg, large bowel resection) at index operation.

Other illness

  • Patients with metastatic disease at presentation.

Other

  • Patients with incomplete data
  • Locally advanced tumor with obvious major vascular involvement requiring complex vascular reconstruction.
  • Uncorrected coagulopathy.
  • Pregnancy or Obese patient (BMI \> 40)
  • Inability to provide informed consent or comply with follow-up.

Who the study is looking for

  • American Society of Anesthesiology score 1-3.
  • Indication for :
    • Simple total nephrectomy or hemi nephrectomy: benign chronic inflammatory non-functioning kidney
    • Partial nephrectomy: localized renal mass ≤7 cm suitable for nephron-sparing surgery.
    • Radical nephrectomy or Radical nephrouretrectomy with bladder cuff: localized renal tumor requiring complete nephrectomy without major vascular invasion.
  • Patient deemed fit for general anesthesia and surgery.
  • Patient provides written informed consent.

Age in the registry: 1 year to - · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Menoufia Faculty of Medicine
Coordinator of this site? Confirm its status
Shibīn al KawmEgyptRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.