NCT07461415Recruiting
Coaching and Navigation by Community Health Workers (CHWs) Through Telehealth for High-risk Hypertension
CONNECT-HTN Trial - Coaching and Navigation by CHWs Through Telehealth for High-risk Hypertension
Source: ClinicalTrials.gov · Last updated 17 Sept 2026
Brief summary (registry, in English)
The investigators propose an intervention that leverages the success of Community Healthcare Workers (CHWs) and telehealth to connect patients with severe hypertension from Emergency Department (ED) to primary care resources and to coach them to adopt evidence-based, practical lifestyle solutions relevant to urban living. The investigators have proposed this intervention as "Coaching and Navigation by Community Health Workers (CHWs) through Telehealth for High-risk Hypertension: CONNECT-HTN intervention. The investigators hypothesize that participants receiving the CONNECT-HTN intervention will have a lower likelihood of experiencing a major cardiac event compared with those referred to clinic-based care.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 3620 (estimated)
- First submitted
- 27 Feb 2026
- Start date
- 16 Mar 2026
- Primary completion date
- Aug 2029
- Lead sponsor
- Weill Medical College of Cornell University
- Diseases
- High blood pressure
- NCT number
- NCT07461415
What you commit to
- Study type: Interventional
- Planned participants: 3620
- From 16 Mar 2026 to the primary completion date, Aug 2029
- 5 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Given that hypertension is defined and treated differently, we will exclude
Other
- pregnant patients
- terminally ill patients, as well as
- those requiring admission to the hospital due to severe complications (other than deranged BP).
Who the study is looking for
- Eligible patients
- Must be over the age of 18 years
- Have an ED triage SBP ≥ 180 and/or DBP ≥ 110, with a repeat similar reading ≥30 minutes after triage
- May have received treatment for elevated BP, but must have no evidence of end-organ damage (defined as dialysis dependence, acute stroke, acute coronary syndrome, acute kidney injury, or papilledema)
- Have a functional status of either fully active (independent in daily activities) or mildly restricted but ambulatory and able to work (washing, toileting, dressing, feeding, mobility).
- May be admitted for deranged BP only with no complications, or may be stable for discharge per treating emergency physician
- Include referrals from the clinic to the ED with SBP/DBP values in the inclusion range
- Can provide informed consent. Intervention is accessible to individuals of all literacy levels
- Can receive phone calls and in-person visits. Smartphone ownership not required (intervention compatible with analog phones)
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (5)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Kharadar General Hospital (KGH) Coordinator of this site? Confirm its status | Karachi | Pakistan | Recruiting |
| Jinnah Postgraduate Medical Center (JPMC) Coordinator of this site? Confirm its status | Karachi | Pakistan | Recruiting |
| Aga Khan University Hospital (AKUH) Coordinator of this site? Confirm its status | Karachi | Pakistan | Recruiting |
| Sindh Institute of Emergency and Health Sciences (SIEHS) Coordinator of this site? Confirm its status | Karachi | Pakistan | Recruiting |
| Dow University Hospital, Ojha Campus Coordinator of this site? Confirm its status | Karachi | Pakistan | Withdrawn |
This page is information, not medical advice. Discuss any trial with your doctor.