NCT07461818Recruiting
Point of Care - Triage and Treatment for Cervical Pre-cancer
POINT of CARE - Providing an Innovative New Triage and Treatment Strategy for Cervical Cancer Screening Efficiency
Source: ClinicalTrials.gov · Last updated 28 Aug 2026
Brief summary (registry, in English)
This study evaluates a modified two-probe thermal ablation protocol using the IRIS™ device and retrospectively assesses an AI-based Automated Visual Evaluation (AVE) triage algorithm among HPV-positive women in El Salvador. The primary objective is to estimate 1-year cure rates of CIN2+ following treatment. A secondary objective is to evaluate the diagnostic performance of AVE compared with histopathology.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 5000 (estimated)
- First submitted
- 5 Mar 2026
- Start date
- 1 Jan 2026
- Primary completion date
- Jan 2029
- Lead sponsor
- Basic Health International, Inc.
- Diseases
- Cervical cancer
- NCT number
- NCT07461818
What you commit to
- Study type: Interventional
- Planned participants: 5000
- From 1 Jan 2026 to the primary completion date, Jan 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of LEEP or cervical ablation procedure in the past 5 years
- History of total hysterectomy (verified by medical record or pelvic evaluation)
- History of cervical cancer
Other
- Plans to become pregnant during the study
- Unable or unwilling to provide a permanent and reliable address
- Unable or unwilling to provide informed consent
Who the study is looking for
- Women aged 30-49 years
- Non-pregnant (determined by urine pregnancy test)
- HPV-positive per Ministry of Health (MOH) records
- Willing to undergo colposcopy and biopsies
- Able and willing to provide informed consent
Age in the registry: 30 years to 49 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Basic Health International Coordinator of this site? Confirm its status | San Salvador | El Salvador | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.