NCT07461870Active, not recruiting
The Mediterranean Diet Based on Local Foods for Obese Patients
The Mediterranean Diet Based on Local Foods for Obese Patients: A Study of Anthropometric Parameters, Inflammatory Markers, and Gut Microbiota
Source: ClinicalTrials.gov · Last updated 10 Mar 2026
Brief summary (registry, in English)
The goal of this clinical trial is to examine the efficacy of a Mediterranean diet based on local Indonesian foods on alterations in gut microbiota, body composition, and metabolic biomarkers in obese subjects. The main questions it aims to answer are: Dose Mediterranean diet modification based on local food ingredients can result in greater weight loss, greater reductions in inflammatory markers, improve gut microbiota diversity compared to a balanced low-calorie diet in obese patients? Researchers will compare Mediterranean diet modification based on local food to low calorie diet. Participant will: * Participants received a low-calorie diet of approximately 1.500 kcal/day according to their randomized group assignments, consisting of breakfast, lunch, dinner, and snacks. Both groups will receive dietary education and physical activity guidance tailored to their weight loss needs. * Participants were instructed to complete a food intake record and report their consumption to the researchers using intake forms and photographs of the food packaging. Weekly meetings were held via Zoom to evaluate dietary compliance. * Blood samples and fecal specimens were collected at baseline (week 0) and at week 4 of the study.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 54 (actual)
- First submitted
- 20 Jan 2026
- Start date
- 9 Dec 2025
- Primary completion date
- 8 Feb 2026
- Lead sponsor
- Universitas Indonesia
- Diseases
- Obesity
- NCT number
- NCT07461870
What you commit to
- Study type: Interventional
- Participants enrolled: 54
- From 9 Dec 2025 to the primary completion date, 8 Feb 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Taking medications with hyperglycemic effects, such as beta-blockers, thiazides, corticosteroids, calcineurin inhibitors, anti-dyslipidemic medications (e.g., statins, fibrates, niacin, and bile acid sequestrants), or antibiotics.
Other illness
- Subjects with a history of type 2 diabetes, kidney disease, liver disease, or thyroid disorders, as indicated by medical history or medical records.
- Contraindications for the MF-BIA examination include the use of pacemakers or implants and a history of amputation.
- History of food allergies
Other
- Pregnant or within 40 days of childbirth
- Adults with edema
Who the study is looking for
- Women who were obese, as defined by a BMI of at least 27.
- Aged 18-50 years
- Subjects with a non-shift work schedule
- Willing to follow the research procedures and sign the informed consent form.
Age in the registry: 18 years to 50 years · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Department of Nutrition, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia Coordinator of this site? Confirm its status | Jakarta Pusat | Indonesia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.