NCT07462611Recruiting
HIV Pre-Exposure Prophylaxis (PrEP) Linkage With Immediate Medications in the Emergency Department Study
HIV Pre-Exposure Prophylaxis (PrEP) Linkage With Immediate Medications in the Emergency Department (PrEP-ED) Study
Source: ClinicalTrials.gov · Last updated 2 Jun 2026
Brief summary (registry, in English)
Our primary objective is to increase HIV pre-exposure prophylaxis (PrEP) awareness and uptake among people who want, need, or would benefit from PrEP in Dallas, TX through a pilot program of immediate PrEP prescribing in the Parkland Memorial Hospital Emergency Department (ED) with linkage to PrEP clinic. Leveraging the previous work of the Parkland Center for Clinical Innovation (PCCI) which created an automated electronic health record (EHR) based HIV prediction tool and prior success with a robust ED HIV navigation program, a PrEP navigator would approach patients in the Parkland ED for PrEP initiation. Through standard care prescribing by their ED clinician, subjects would leave the ED with a prescription for rapid-start oral PrEP and a clinic appointment to persist on the PrEP modality of their choice which will include long-acting injectable options.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 250 (estimated)
- First submitted
- 2 Mar 2026
- Start date
- 8 Apr 2026
- Primary completion date
- 31 Oct 2027
- Lead sponsor
- University of Texas Southwestern Medical Center
- Diseases
- HIV
- NCT number
- NCT07462611
What you commit to
- Study type: Interventional
- Planned participants: 250
- From 8 Apr 2026 to the primary completion date, 31 Oct 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Known diagnosis of HIV
- Positive HIV rapid test
- Known hypersensitivity or allergy to any PrEP modality
Age
- Adults unable to consent, people under the age of 18, women who are known to be pregnant or breast feeding at time of study enrollment, or prisoners
- Sub-study subjects (ED clinicians):
- People under the age of 18 or prisoners.
Other
- Current use of PrEP, which is defined for purposes of this study as use of PrEP in the last 4 weeks
- People who do not want to follow with Parkland ID clinic for ongoing PrEP care
Who the study is looking for
- Able to comprehend and provide signed, written informed consent prior to initiation of study procedures.
- Negative HIV rapid test
- At least one of the following criteria:
- Requesting PrEP from their ED clinician
- Score \>75% on the PCCI HIV Prediction Tool
- Prior bacterial STI diagnosis
- Seeking STI testing
- Referred by their ED clinician as someone who otherwise meets a CDC PrEP indication
- Clinician in the Parkland ED
Criteria the registry did not label
- Primary study (ED patients):
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Parkland Health Coordinator of this site? Confirm its status | Dallas | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.