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NCT07462767RecruitingPhase 1/2

Precision Microbiota Interventions for Senoreduction Trial

Geroprotective Precision Medicine Strategies in PWH That Use Alcohol

Source: ClinicalTrials.gov · Last updated 29 Oct 2026

Brief summary (registry, in English)

People with HIV who drink alcohol are at increased risk for accelerated aging biology, including increased immune senescence. This randomized, double-blind, crossover clinical trial evaluates two generally recognized as safe (GRAS) microbiota-targeted interventions on immune senescence biomarkers.

Status (registry)
Recruiting
Phase (registry)
Phase 1/2
Study type
Interventional
Enrollment
160 (estimated)
First submitted
22 Feb 2026
Start date
1 Sept 2026
Primary completion date
1 Dec 2029
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Diseases
HIV
NCT number
NCT07462767

What you commit to

  • Study type: Interventional · Phase 1/2
  • Planned participants: 160
  • From 1 Sept 2026 to the primary completion date, 1 Dec 2029
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Allergy to study products

Other

  • Probiotic use in past 3 months
  • Recent antibiotics or immunosuppressives
  • Pregnancy or breastfeeding
  • Inability to comply

Who the study is looking for

  • Age ≥40 years
  • People with HIV
  • Recent alcohol use defined as ≥42 grams in the prior week and positive urine ethyl glucuronide (EtG)

Age in the registry: 40 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
LSU Health
Coordinator of this site? Confirm its status
New OrleansUnited StatesRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.