NCT07463859Recruiting
Effects of Periodontal Treatment Associated With Antimicrobial Photodynamic Therapy on Halitosis in Patients With Diabetes Mellitus
Effects of Periodontal Treatment Associated With Antimicrobial Photodynamic Therapy on Halitosis in Patients With Diabetes Mellitus: A Randomized Clinical Trial
Source: ClinicalTrials.gov · Last updated 16 Mar 2026
Brief summary (registry, in English)
The goal of this clinical trial is to evaluate the effectiveness of periodontal treatment associated with the use of a tongue scraper, compared with the same treatment combined with antimicrobial photodynamic therapy (aPDT), in reducing halitosis in individuals with periodontal disease and type 2 diabetes mellitus. The main question it aims to answer is: aPDT treatment is more effective in treating halitosis? aPDT treatment is more effective in periodontitis? Researchers will compare aPDT treatment to conventional treatment (scaling and root planning and tongue scraper) to see if aPDT has additional effects in reducing halitosis and improving periodontal health. * Participants will be asked to visit the clinic once a week for exam and treatment during 1 month. * After active treatment they will be asked to come to maintenance and control visits once a month until 6 months.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 32 (estimated)
- First submitted
- 5 Mar 2026
- Start date
- 2 Apr 2026
- Primary completion date
- 31 Jan 2027
- Lead sponsor
- University of Sao Paulo
- Diseases
- Type 2 diabetes
- NCT number
- NCT07463859
What you commit to
- Study type: Interventional
- Planned participants: 32
- From 2 Apr 2026 to the primary completion date, 31 Jan 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients using medications that affect the periodontium
Other illness
- Patients with renal disorders
Other
- Smokers
- Alcohol-dependent individuals
- Pregnant or lactating women
Who the study is looking for
- Patients diagnosed with type 2 diabetes mellitus according to the 2019 WHO criteria
- Stage 3 or 4 periodontitis
- No periodontal treatment in the previous 12 months
- a minimum of 20 remaining teeth.
Age in the registry: 18 years to 70 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Bauru School of Dentistry Coordinator of this site? Confirm its status | Bauru | Brazil | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.