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NCT07463859Recruiting

Effects of Periodontal Treatment Associated With Antimicrobial Photodynamic Therapy on Halitosis in Patients With Diabetes Mellitus

Effects of Periodontal Treatment Associated With Antimicrobial Photodynamic Therapy on Halitosis in Patients With Diabetes Mellitus: A Randomized Clinical Trial

Source: ClinicalTrials.gov · Last updated 16 Mar 2026

Brief summary (registry, in English)

The goal of this clinical trial is to evaluate the effectiveness of periodontal treatment associated with the use of a tongue scraper, compared with the same treatment combined with antimicrobial photodynamic therapy (aPDT), in reducing halitosis in individuals with periodontal disease and type 2 diabetes mellitus. The main question it aims to answer is: aPDT treatment is more effective in treating halitosis? aPDT treatment is more effective in periodontitis? Researchers will compare aPDT treatment to conventional treatment (scaling and root planning and tongue scraper) to see if aPDT has additional effects in reducing halitosis and improving periodontal health. * Participants will be asked to visit the clinic once a week for exam and treatment during 1 month. * After active treatment they will be asked to come to maintenance and control visits once a month until 6 months.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
32 (estimated)
First submitted
5 Mar 2026
Start date
2 Apr 2026
Primary completion date
31 Jan 2027
Lead sponsor
University of Sao Paulo
NCT number
NCT07463859

What you commit to

  • Study type: Interventional
  • Planned participants: 32
  • From 2 Apr 2026 to the primary completion date, 31 Jan 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Patients using medications that affect the periodontium

Other illness

  • Patients with renal disorders

Other

  • Smokers
  • Alcohol-dependent individuals
  • Pregnant or lactating women

Who the study is looking for

  • Patients diagnosed with type 2 diabetes mellitus according to the 2019 WHO criteria
  • Stage 3 or 4 periodontitis
  • No periodontal treatment in the previous 12 months
  • a minimum of 20 remaining teeth.

Age in the registry: 18 years to 70 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Bauru School of Dentistry
Coordinator of this site? Confirm its status
BauruBrazilRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.