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NCT07464106Recruiting

Evaluation of the Impact of Interventional Treatments for Symptomatic, Severe Tricuspid Valve Insufficiency on Renal Integrity and Function, as Well as on Physical Function and Activity in Older Adults.

Source: ClinicalTrials.gov · Last updated 11 Mar 2026

Brief summary (registry, in English)

The hypothesis is that renal function will improve following tricuspid valve intervention. A reduction in renal biomarkers is also expected. Furthermore, based on previous assessments, it is anticipated that there will be an improvement in volume status (reduced edema), symptom burden, and physical capacity in patients. Additionally, the study will assess the impact of the intervention on functional parameters such as motor capacity, physical activity, performance of activities of daily living, and ultimately, participation and quality of life.

Status (registry)
Recruiting
Study type
Observational
Enrollment
100 (estimated)
First submitted
21 Jul 2025
Start date
1 Feb 2025
Primary completion date
31 Dec 2026
Lead sponsor
Robert Bosch Medical Center
NCT number
NCT07464106

What you commit to

  • Study type: Observational
  • Planned participants: 100
  • From 1 Feb 2025 to the primary completion date, 31 Dec 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Dialysis-dependent/terminal kidney disease
  • Inability to comply with study-associated assessments (e.g., existing dementia)

Lab values

  • Severe anemia (Hb \<7 g/dl)

Other

  • Tricuspid valve intervention with palliative intent and likely imminent death
  • Lack of consent

Who the study is looking for

  • Severe symptomatic tricuspid valve insufficiency and referral for TriClip/TricValve screening
  • Completed 18th year of life
  • Ability to consent
  • Able to walk short distances with aids

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Robert-Bosch-Hospital
Coordinator of this site? Confirm its status
StuttgartGermanyRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.