NCT07464522Not yet recruiting
Non-invasive Predictors of Esophageal Varices and Their Correlation to Upper Endoscopic Findings
Non-invasive Predictors of Esophageal Varices in Pediatric Portal Hypertension and Their Correlation to Upper Endoscopic Findings
Source: ClinicalTrials.gov · Last updated 23 Mar 2026
Brief summary (registry, in English)
The goal of this observational study: * To evaluate the diagnostic accuracy of non-invasive markers in predicting the presence and grading of esophageal varices in children with portal hypertension. * To correlate these non-invasive markers with the severity of portal hypertension and the grade of esophageal varices to identify patients at high risk of bleeding. * To propose a defined protocol for screening esophageal varices in those children.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 51 (estimated)
- First submitted
- 2 Mar 2026
- Start date
- Mar 2026
- Primary completion date
- Mar 2028
- Lead sponsor
- Assiut University
- Diseases
- High blood pressure
- NCT number
- NCT07464522
What you commit to
- Study type: Observational
- Planned participants: 51
- From Mar 2026 to the primary completion date, Mar 2028
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous history of variceal bleeding or endoscopic intervention (band ligation/sclerotherapy).
- Prior surgical portosystemic shunts or Transjugular Intrahepatic Portosystemic Shunt (TIPS).
- Current use of vasoactive drugs for primary prophylaxis (e.g., Non-selective beta-blockers).
Lab values
- Active variceal bleeding at presentation (hemodynamic instability affects platelet/spleen parameters).
- Systemic infections or hematological disorders causing independent thrombocytopenia or splenomegaly (to avoid confounding the platelet/spleen ratio).
Who the study is looking for
- Patients aged less than 18 years diagnosed with portal hypertension either due to hepatic or extrahepatic causes
Age in the registry: - to 18 years · Sex: All · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.