NCT07467018Recruiting
Mobile Vehicle-Based Delivery of Lenacapavir Pre-Exposure Prophylaxis in Los Angeles County
Mobile Vehicle-Based Delivery of Lenacapavir Pre-Exposure Prophylaxis in Los Angeles County (MOVE-LA)
Source: ClinicalTrials.gov · Last updated 23 Apr 2026
Brief summary (registry, in English)
This project evaluates the implementation strategy of the delivery of lenacapavir pre-exposure prophylaxis (LEN PrEP) - a newly available long-acting, injectable medication for human immunodeficiency virus (HIV) prevention - via a mobile health van model for people who are unstably housed in Los Angeles County (LAC). People who are unhoused or are facing housing instability experience significant barriers to accessing HIV prevention care in traditional clinic settings. In 2022, approximately 13% of newly diagnosed HIV cases in LAC were experiencing homelessness, a 36% increase over the prior period. The study will work with the University of California, Los Angeles (UCLA) Health's Homeless Healthcare Collaborative (HHC), which operates mobile health vans staffed by clinicians, social workers, and community health workers, to bring LEN PrEP directly to community settings, such as shelters, encampments, community centers, and transitional housing facilities. This study has three primary aims: 1. Characterize uptake of LEN PrEP among unstably housed people in LAC receiving health services via HHC's mobile program. 2. Evaluate how many study participants stay on LEN PrEP through 52 weeks. 3. Understand costs, acceptability, and sustainability of the mobile LEN PrEP delivery model.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 100 (estimated)
- First submitted
- 7 Mar 2026
- Start date
- 21 Apr 2026
- Primary completion date
- 31 Dec 2026
- Lead sponsor
- University of California, Los Angeles
- Diseases
- HIV
- NCT number
- NCT07467018
What you commit to
- Study type: Observational
- Planned participants: 100
- From 21 Apr 2026 to the primary completion date, 31 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Any clinical or psychosocial condition or prior therapy that, in the opinion of the investigator, would make the participant unsuitable for the study or unable to take LEN PrEP
Other illness
- Known hypersensitivity to the study drug, the metabolites, or formulation excipient
- Already taking LEN for HIV prevention
- Known HIV diagnosis or positive 4th generation HIV Ab/Ag test (on day of enrollment) or subsequent lab-based confirmatory testing.
Other
- BMI \<35 kg/m2 (77 pounds)
- On oral or other long-acting PrEP and unwilling to discontinue
Who the study is looking for
- Being reached for mobile health services by a UCLA HHC mobile van
- ≥18 years of age
- Able to provide informed consent
- English or Spanish-speaking
- Willing and able to comply with study procedures
- HIV unknown or negative status and HIV negative based on rapid 4th generation Ag/Ab test on the day of enrollment
- At-risk for HIV, based on clinician assessment (based on CDC guidelines; includes any individual requesting PrEP, regardless of reported risk factors for HIV)
- Pregnant and breastfeeding women/people can be offered LEN with counseling about benefits and risks.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| UCLA Health Homeless Healthcare Collaborative Coordinator of this site? Confirm its status | Santa Monica | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.