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NCT07468656Not yet recruiting

SCLC Tarlatamab Blood Collection

Analysis of Blood Samples in Small Cell Lung Cancer Patients Treated With Tarlatamab

Source: ClinicalTrials.gov · Last updated 5 Aug 2026

Brief summary (registry, in English)

The overall objective of this project is to prospectively collect blood samples throughout treatment with tarlatamab in patients with small cell lung cancer (SCLC). These samples will then be analyzed through a variety of assays to better characterize tarlatamab in the real-world setting. The investigators will prospectively collect blood samples from 25 patients on days 1, 8, and 15 of tarlatamab treatment, as well as after each interval scan for disease monitoring. The investigators will also collect patient data including demographics and baseline characteristics, primary diagnosis, treatment history, and disease monitoring and progression.

Status (registry)
Not yet recruiting
Study type
Observational
Enrollment
25 (estimated)
First submitted
9 Mar 2026
Start date
Oct 2026
Primary completion date
Dec 2028
Lead sponsor
Duke University
Diseases
Lung cancer
NCT number
NCT07468656

What you commit to

  • Study type: Observational
  • Planned participants: 25
  • From Oct 2026 to the primary completion date, Dec 2028
  • No sites listed in no country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • Does not meet all inclusion criteria

Who the study is looking for

  • Pathologically documented small cell lung cancer (SCLC) or neuroendocrine tumor
  • Appropriate candidate for treatment with tarlatamab based on investigator discretion
  • Age \> 18 years
  • Signed written informed consent including HIPAA according to institutional guidelines

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

This page is information, not medical advice. Discuss any trial with your doctor.