NCT07469280Not yet recruiting
High-Intensity Progressive Inspiratory Muscle Training in Class III Obesity and Obstructive Sleep Apnea
High-Intensity Progressive Inspiratory Muscle Training in Class III Obesity and Obstructive Sleep Apnea: Study Protocol for a Prospective Nonconcurrent Multiple-Baseline Single-Case Experimental Design With Stability-Based Phase Transition
Source: ClinicalTrials.gov · Last updated 23 Mar 2026
Brief summary (registry, in English)
The purpose of this study is to evaluate the feasibility and effects of a 12-week high-intensity progressive Inspiratory Muscle Training (IMT) program in individuals with Class III obesity (BMI ≥ 40 kg/m²) and obstructive sleep apnea (OSA). Using a single-case experimental design (SCED) with multiple baselines, the study will investigate whether this respiratory intervention can reduce the severity of sleep apnea, as measured by the Apnea-Hypopnea Index (AHI), and improve inspiratory muscle strength and sleep quality. Participants will perform daily training sessions using a resistive loading device (POWERbreathe), with intensity progressing from 40% to 90% of their maximum inspiratory pressure.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 10 (estimated)
- First submitted
- 9 Mar 2026
- Start date
- 1 May 2026
- Primary completion date
- 1 May 2027
- Lead sponsor
- University of the State of Santa Catarina
- Diseases
- Obesity
- NCT number
- NCT07469280
What you commit to
- Study type: Interventional
- Planned participants: 10
- From 1 May 2026 to the primary completion date, 1 May 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Are using medications that may affect muscle performance.
- Are currently using CPAP therapy.
Other illness
- Systemic diseases (pulmonary, cardiac or renal).
- Conditions that could compromise adherence to the study protocol.
Who the study is looking for
- Of both genders.
- Class III obesity (BMI \> 40 kg/m²).
- Diagnosis of OSA.
- Without neurological conditions that would prevent them from responding to the study assessments.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Santa Catarina State University - CEFID (Center of Health and Sport Sciences) Coordinator of this site? Confirm its status | Florianópolis | Brazil | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.