NCT07471022Completed
Hemiarthroplasty for Elderly With Proximal Humeral Mets
The Application of Hemiarthroplasty in Elderly Patients With Proximal Humeral Metastases
Source: ClinicalTrials.gov · Last updated 13 Mar 2026
Brief summary (registry, in English)
Bone metastases are common in patients with advanced cancer and frequently involve the proximal humerus, leading to severe pain and loss of shoulder function. Shoulder arthroplasty is an important surgical option for restoring limb function and relieving pain in these patients. However, elderly patients often have multiple comorbidities, and it remains unclear whether age affects surgical outcomes and prognosis after arthroplasty for proximal humeral metastases. This retrospective observational study reviewed patients with isolated proximal humeral metastases who underwent shoulder arthroplasty at our institution. Patients were divided into elderly and younger groups based on age, and clinical outcomes were compared between the groups. Evaluated outcomes included operative characteristics, postoperative pain, limb function, complications, survival, recurrence, and quality of life. The aim of this study is to determine whether age influences prognosis and functional recovery after shoulder arthroplasty for proximal humeral metastases, and to assess the feasibility and effectiveness of this surgical procedure in elderly patients.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 53 (actual)
- First submitted
- 10 Mar 2026
- Start date
- 1 Jan 2013
- Primary completion date
- 31 Dec 2021
- Lead sponsor
- Sichuan Provincial People's Hospital
- Diseases
- Childhood cancers
- NCT number
- NCT07471022
What you commit to
- Study type: Observational
- Participants enrolled: 53
- From 1 Jan 2013 to the primary completion date, 31 Dec 2021
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patients with multiple bone metastases involving two or more skeletal sites.
- Metastatic lesions affecting the scapula, axillary nerve, or brachial plexus.
- Death during the perioperative period.
- Presence of three or more significant comorbidities, such as uncontrolled diabetes, severe cardiopulmonary disease, or chronic renal failure.
- Loss to follow-up within 3 months after surgery.
Who the study is looking for
- Patients with a single metastatic lesion in the proximal humerus, confirmed by imaging or biopsy.
- Presence of pathological fracture or a severe osteolytic lesion at risk of fracture (Mirels score ≥9).
- Poor response to radiotherapy according to RECIST 1.1 criteria.
- Persistent severe shoulder pain or significant loss of shoulder function.
- Estimated life expectancy \>3 months at the time of surgery..
Sex: All · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.