NCT07472686Recruiting
Small Bowel Capsule Endoscopy in Lynch Syndrome
Small Bowel Capsule Endoscopy for (Pre)Neoplastic Lesion Screening in Patients With Lynch Syndrome
Source: ClinicalTrials.gov · Last updated 16 Mar 2026
Brief summary (registry, in English)
The impact of small bowel (SB) capsule endoscopy (CE) on the screening (followed by diagnosis and treatment) of (pre)neoplastic lesions of the small bowel in Lynch syndrome (LS) patients is unknown. The iCARE4Lynch study is a retrospective cohort of patients carrying a pathogenic variant of the DNA mismatch repair gene (MMR) (MLH1, MSH2, MSH6, PMS2, EPCAM) who had had at least one SBCE for screening of small bowel (pre)neoplastic lesions between January 1st 2000 and December 31 2024.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 400 (estimated)
- First submitted
- 27 Feb 2026
- Start date
- 16 Jun 2025
- Primary completion date
- Jun 2026
- Lead sponsor
- Assistance Publique - Hôpitaux de Paris
- Diseases
- Colorectal cancer
- NCT number
- NCT07472686
What you commit to
- Study type: Observational
- Planned participants: 400
- From 16 Jun 2025 to the primary completion date, Jun 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Absence of documented MMR gene variant
- Opposition to the study
Who the study is looking for
- Patient carrying a pathogenic variant of the DNA mismatch repair gene (MMR) (MLH1, MSH2, MSH6, PMS2, EPCAM)
- Capsule endoscopy screening for (pre)neoplastic lesions of the small intestine
- No opposition to the reuse of healthcare data for research purposes
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Center for Digestive Endoscopy, Saint-Antoine Hospital Coordinator of this site? Confirm its status | Paris | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.