NCT07474129Not yet recruiting
Serious Game Rehabilitation and Brain Plasticity in MS
Brain Reorganization After Serious Game -Based Cognitive Rehabilitation in Multiple Sclerosis
Source: ClinicalTrials.gov · Last updated 16 Mar 2026
Brief summary (registry, in English)
This prospective, interventional, longitudinal, multicentre study aims to evaluate the impact of the "Serious game", an innovative cognitive remediation tool on brain reorganization in Multiple sclerosis patients, using functional Magnetic resonance imaging (MRI). The serious game is a tool combining the motivational mechanisms of video games with cognitive remediation techniques.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- First submitted
- 11 Mar 2026
- Start date
- 1 Jun 2026
- Primary completion date
- 31 Mar 2030
- Lead sponsor
- Lille Catholic University
- Diseases
- Multiple sclerosis
- NCT number
- NCT07474129
What you commit to
- Study type: Interventional
- Planned participants: 40
- From 1 Jun 2026 to the primary completion date, 31 Mar 2030
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Neurological or psychiatric comorbidity, other than MS and anxiety-depression syndrome,
- Patient with severe anxiety-depression syndrome (BDI-FS \> 10),
Other
- Claustrophobia preventing MRI;
- Contraindication to MRI;
- Wearing fixed dental braces;
- Unable to receive oral and written information;
- Unable to use the software (due in particular to motor and/or sensory difficulties);
- Pregnant or breastfeeding women
- Taking neuroleptic treatment
- Person under guardianship or curatorship
- Person deprived of liberty
Who the study is looking for
- People with relapsing-remitting or progressive MS defined according to the 2010 revised McDonald criteria \[56\]
- Cognitive complaints and deficits in at least one score on the initial neuropsychological examination (\<5th percentile of the reference group)
- Aged between ≥ 18 and ≤ 65 years
- No defined relapse for at least 6 weeks
- At least 4 weeks since a corticosteroid bolus
- Patient with an internet connection
- Patient covered by social security
- Signed informed consent
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.