NCT07475936Recruiting
Intravenous Tenecteplase in Very Old Patients With Acute Ischemic Stroke
A Multicenter, Prospective, Observational, Real-World Registry Study of Intravenous Tenecteplase in Very Old Patients With Acute Ischemic Stroke
Source: ClinicalTrials.gov · Last updated 31 Aug 2026
Brief summary (registry, in English)
The benefit of intravenous tenecteplase in very old patients with acute ischemic stroke (AIS) remain uncertain. This real-world study aims to evaluate the effectiveness and safety of intravenous tenecteplase in AIS patients aged 80 years or older within 4.5 hours of symptom onset.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 392 (estimated)
- First submitted
- 13 Mar 2026
- Start date
- 22 Mar 2026
- Primary completion date
- Dec 2027
- Lead sponsor
- First Affiliated Hospital of Guangxi Medical University
- Diseases
- Stroke
- NCT number
- NCT07475936
What you commit to
- Study type: Observational
- Planned participants: 392
- From 22 Mar 2026 to the primary completion date, Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous treatment with other thrombolytic agents such as alteplase, urokinase, plasminogen activator, or reteplase;
Other illness
- The investigator deems the patient unsuitable for this study or the study might pose significant risk to the patient (e.g., due to psychiatric disorders, cognitive or emotional impairments that prevent understanding or adherence to study procedures and/or follow-up).
Age
- Any contraindication to intravenous thrombolysis (excluding age);
Other
- Current participation in other interventional studies;
Who the study is looking for
- Age \> 80 years;
- Clinically diagnosed with acute ischemic stroke and arrived at the hospital within 4.5 hours of symptom onset;
- Informed consent signed by the patient or legally authorized representative.
Age in the registry: 80 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The First Affiliated Hospital of Guangxi Medical University Coordinator of this site? Confirm its status | Nanning | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.