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NCT07478146Recruiting

Brief Title: Aerobic Training on Cerebrovascular Function, Cognition and Gait in Parkinson's Disease

Effects of Aerobic Training on Cerebrovascular Function, Cognitive Performance and Gait Parameters in Patients With Parkinson's Disease: A Randomized Controlled Trial

Source: ClinicalTrials.gov · Last updated 13 Apr 2026

Brief summary (registry, in English)

This randomized controlled trial will investigate the effects of a 12-week supervised aerobic training program on cerebrovascular function, peripheral vascular health, cardiovascular autonomic modulation, cognition, non-motor symptoms, sleep, mood, gait biomechanics, quality of life, and body composition in patients with Parkinson's disease (Hoehn \& Yahr stages 1-3). Participants will be randomly allocated to aerobic training or usual care.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
40 (estimated)
First submitted
27 Feb 2026
Start date
28 Feb 2026
Primary completion date
30 Jun 2027
Lead sponsor
Raphael Mendes Ritti Dias
NCT number
NCT07478146

What you commit to

  • Study type: Interventional
  • Planned participants: 40
  • From 28 Feb 2026 to the primary completion date, 30 Jun 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study design.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Change in medication

Other

  • Contraindication to exercise

Who the study is looking for

  • Clinical diagnosis of Parkinson's disease
  • Hoehn \& Yahr stages 1-3
  • Stable antiparkinsonian medication for at least 4 weeks
  • Montreal Cognitive Assessment (MoCA) score ≥ 18
  • Ability to walk independently (with or without assistive device)
  • Medical clearance for participation in moderate-intensity exercise

Age in the registry: 40 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Save your city in your profile to sort them by distance.

SiteCityCountrySite status
Associação Brasil Parkinson
Coordinator of this site? Confirm its status
São PauloBrazilRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.