NCT07478653Recruiting
MODERN-Dental: Pediatric Obesity, Cardiometabolic Risks, And Periodontal Disease
MODERN-Dental: Pediatric Obesity, Cardiometabolic Risks, And Periodontal Disease: Effects Of Semaglutide Treatment
Source: ClinicalTrials.gov · Last updated 8 Oct 2026
Brief summary (registry, in English)
The goal of this clinical trial is to assess whether adjunctive dental cleaning can enhance the effects of semaglutide in children with obesity. The main question\[s\] it aims to answer \[is/are\]: if dental cleaning will improve both oral health and metabolic outcomes beyond the effects of semaglutide alone. Participants will receive either dental cleaning and oral hygiene instruction or oral hygiene instruction alone.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 50 (estimated)
- First submitted
- 12 Mar 2026
- Start date
- 31 Aug 2026
- Primary completion date
- 31 Jul 2028
- Lead sponsor
- Oelisoa Andriankaja
- Diseases
- Obesity
- NCT number
- NCT07478653
What you commit to
- Study type: Interventional
- Planned participants: 50
- From 31 Aug 2026 to the primary completion date, 31 Jul 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of any anti-inflammatory medication (other than steroids) within 1 month prior to enrollment
- Currently taking medications that could influence the characteristics or response to periodontal treatment (e.g., use of immunosuppressants or steroids)
- Local or systemic antibiotic use within 15 days prior to enrollment or for \>10 days within the past 3 months
- Professional dental prophylaxis or non-surgical periodontal therapy within the past 6 months
Other illness
- History of bleeding disorders
Other
- Same exclusion as parent study.
- Planning to receive or complete dental services during the 12-month course of the study
- Ongoing orthodontic treatment
Who the study is looking for
- participants from the ongoing Mitigation of Cardiovascular Disease Risks in Children with Extreme Obesity (MODERN) study (NCT06967389)
- Class 2 or 3 obesity (BMI =120% of the 95th percentile for age and sex)
Age in the registry: 12 years to 17 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Kentucky Coordinator of this site? Confirm its status | Lexington | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.