NCT07478757Not yet recruiting
Assessing the Effectiveness of Low-Dose Computed Tomography in Lung Cancer Screening for High-Risk Smokers: A Randomized Controlled Trial in Hong Kong
Source: ClinicalTrials.gov · Last updated 17 Mar 2026
Brief summary (registry, in English)
The investigators propose a randomized controlled trial to evaluate the clinical effectiveness of low-dose computed tomography (LDCT) for lung cancer screening in high-risk Chinese ever-smokers aged 50-79 years in Hong Kong and to assess the cost-effectiveness of implementing LDCT for lung cancer screening in the local setting.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 15000 (estimated)
- First submitted
- 12 Mar 2026
- Start date
- 1 Jul 2026
- Primary completion date
- 30 Jun 2032
- Lead sponsor
- The University of Hong Kong
- Diseases
- Lung cancer
- NCT number
- NCT07478757
What you commit to
- Study type: Interventional
- Planned participants: 15000
- From 1 Jul 2026 to the primary completion date, 30 Jun 2032
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Individuals with a known prior diagnosis of lung cancer or detection of lung nodules
- Individuals who have undergone a CT scan of the thorax in the previous 12 months
Other illness
- Individuals who are not mentally competent to provide informed consent (e.g., those with a history of dementia)
- Individuals with a history of other cancers within the last five years or currently under treatment
- Individuals who are either unwilling to undergo a chest LDCT scan, or having a condition that prevents them from having a LDCT scan (for example, pregnancy or inability to lie flat on the CT table)
Other
- Non-Chinese population
Who the study is looking for
- Adults aged between 50 and 79 years
- Current smokers or ex-smokers quitted for less than 10 years, with a history of cigarette smoking equivalent to at least 20 pack-years
Age in the registry: 50 years to 79 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| School of Public Health, The University of Hong Kong Coordinator of this site? Confirm its status | Hong Kong | Hong Kong SAR China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.