NCT07479329Not yet recruiting
Estimated Risk of Preeclampsia in the First Trimester and Its Association With Subclinical Atherosclerosis and Cardiovascular Risk in Women With Type 1 Diabetes
Source: ClinicalTrials.gov · Last updated 18 Mar 2026
Brief summary (registry, in English)
This multicenter observational cohort study aims to evaluate whether estimated first-trimester risk of preeclampsia (PE) is associated with subclinical atherosclerosis, cardiovascular risk profile, and cardiovascular events in women with type 1 diabetes (T1D) at least 3 years after pregnancy. Women with T1D and at least one prior pregnancy with documented first-trimester PE screening will be classified as high or low PE risk according to validated multivariable algorithms. The presence of carotid plaques, cardiometabolic risk factors, and incident cardiovascular events will be assessed during a study visit.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 1300 (estimated)
- First submitted
- 3 Mar 2026
- Start date
- 10 Apr 2026
- Primary completion date
- 30 Apr 2028
- Lead sponsor
- Institut d'Investigacions Biomèdiques August Pi i Sunyer
- Diseases
- Type 1 diabetes
- NCT number
- NCT07479329
What you commit to
- Study type: Observational
- Planned participants: 1300
- From 10 Apr 2026 to the primary completion date, 30 Apr 2028
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous multiple pregnancy
Other illness
- Cardiovascular disease before pregnancy (coronary heart disease, stroke/TIA, peripheral artery disease, heart failure)
- Active severe psychiatric disease, dementia, severe disability, or reduced life expectancy
Other
- Active pregnancy at time of evaluation
- Alcohol or substance dependence (except nicotine/caffeine) in the last 3 years
Who the study is looking for
- Age ≥ 18 years
- Confirmed diagnosis of type 1 diabetes
- At least one prior pregnancy with first-trimester preeclampsia screening (\<14 weeks gestation)
- ≥3 years since last pregnancy
Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hospital Clinic Barcelona Coordinator of this site? Confirm its status | Barcelona | Spain | Unknown status |
| Hospital Universitari Mutua Terrassa Coordinator of this site? Confirm its status | Terrassa | Spain | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.