NCT07480785Recruiting
TEAS Combined With Triple Antiemetic Drugs to Prevent PONV in High-Risk Patients
Transcutaneous Electrical Acupoint Stimulation Combined With Triple Antiemetic Drugs for Postoperative Nausea and Vomiting in High-Risk Patients: A Multicenter Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 18 Mar 2026
Brief summary (registry, in English)
The goal of this clinical trial is to evaluate the effects of transcutaneous electrical acupoint stimulation (TEAS) combined with triple antiemetics for postoperative nausea and vomiting (PONV) in high-risk patients. The primary question it seeks to answer is: Does TEAS combined with triple antiemetics further reduce the incidence of PONV in high-risk subjects? Researchers will compare active TEAS with sham stimulation to determine whether the addition of TEAS to dexamethasone, palonosetron, and droperidol lowers the PONV rate beyond that achieved by the triple-drug prophylaxis alone.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 780 (estimated)
- First submitted
- 23 Feb 2026
- Start date
- 16 Jan 2026
- Primary completion date
- 31 Oct 2027
- Lead sponsor
- Zhejiang University
- Diseases
- Ovarian cancer
- NCT number
- NCT07480785
What you commit to
- Study type: Interventional
- Planned participants: 780
- From 16 Jan 2026 to the primary completion date, 31 Oct 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients with a history of allergy to the investigational drug or contraindications；
- Nausea/vomiting or use of antiemetics, opioids, or systemic corticosteroids within 24 h before surgery；
Other illness
- Severe renal or hepatic impairment ；
- Psychiatric or neurological disorder ；
- Vertebrobasilar insufficiency；
- Vestibular disease；
- Skin lesion or infection at the acupoint stimulation site ；
- Implanted cardiac pacemaker or defibrillator ；
Lab values
- Long-QT syndrome ；
Other
- Pregnancy, lactation, or menstruation ；
- Current smoker；
- Requirement for post-operative sedation and mechanical ventilation ；
- Language or communication barrier ；
- Upper-limb nerve injury ；
- Participation in another clinical trial within the past 4 weeks.
Who the study is looking for
- Women scheduled for laparoscopic surgery ；
- Aged 18-65 years；
- ASA Class I-III；
- Apfel score ≥ 3 (female sex, non-smoker, history of PONV and/or motion sickness).
Age in the registry: 18 years to 65 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The First Affiliated Hospital Zhejiang University School of Medicine Coordinator of this site? Confirm its status | Hangzhou | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.