NCT07482618Active, not recruiting
Evaluation of Spasticity, Neuropathic Pain, and Gait Analysis in Stroke Patients Receiving Tolperison Therapy After Botulinum Toxin Injection
Evaluation of Spasticity, Neuropathic Pain, and Gait Analysis in Stroke Patients Receiving Tolperison Therapy After Botulinum Toxin Injection: A Controlled Study
Source: ClinicalTrials.gov · Last updated 20 Mar 2026
Brief summary (registry, in English)
Tolperison is an antispastic agent used in the treatment of spasticity. Studies on tolperison are limited, and the literature on its effectiveness against spasticity and neuropathic pain is also limited.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 40 (estimated)
- First submitted
- 4 Feb 2026
- Start date
- 13 Aug 2025
- Primary completion date
- 25 May 2026
- Lead sponsor
- Ayse Guc
- Diseases
- Stroke
- NCT number
- NCT07482618
What you commit to
- Study type: Observational
- Planned participants: 40
- From 13 Aug 2025 to the primary completion date, 25 May 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- people who have undergone orthopedic surgery
- Those receiving oral antispastic treatment (non-tolperison medications)
- Those who have undergone surgery for spasticity
- Those undergoing surgery, such as with intrathecal baclofen
- Individuals receiving medical treatment for neuropathic pain
Other illness
- Diabetes patients
- Individuals with non-stroke neurological diseases
- History of allergy or hypersensitivity to the medication to be used
Age
- Individuals under 18 and over 80 years of age
Other
- Individuals lacking orientation and cooperation
- Presence of a fixed contracture in the affected extremity
Who the study is looking for
- Ability to stand
- History of previous hemorrhagic or ischemic stroke
- Stroke-related spasticity (MAS ≥2)
- Men and women aged 18-80 years
- Agreement to participate in the study
Age in the registry: 18 months to 80 months · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Kayseri City Hospital Physical Medicine and Rehabilitation Coordinator of this site? Confirm its status | Kayseri | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.